Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb
about
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genesAcetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cellsSystematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzymeCracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFbHMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription.Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator TatReconstitution of a functional 7SK snRNPGenetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells.Mutation of the HEXIM1 gene results in defects during heart and vascular development partly through downregulation of vascular endothelial growth factor.Nuclear organization and dynamics of 7SK RNA in regulating gene expression.HEXIM1 targets a repeated GAUC motif in the riboregulator of transcription 7SK and promotes base pair rearrangementsRNA polymerase II transcription elongation control.The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiationHexim1 sequesters positive transcription elongation factor b from the class II transactivator on MHC class II promoters.HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells.PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.PKC phosphorylates HEXIM1 and regulates P-TEFb activity.The CD8+ cell non-cytotoxic antiviral response affects RNA polymerase II-mediated human immunodeficiency virus transcription in infected CD4+ cellsFunctional interplay between PPM1G and the transcription elongation machinery.7SKiing on chromatin: Move globally, act locally.Steps towards a repertoire of comprehensive maps of human protein interaction networks: the Human Proteotheque Initiative (HuPI)The MORC family: new epigenetic regulators of transcription and DNA damage response.Transcription elongation control by the 7SK snRNP complex: Releasing the pause.HEXIM1, a New Player in the p53 PathwayP-TEFb- the final frontier.U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex.Invertebrate 7SK snRNAs.Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvaeRelease of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.CYCLINg through transcription: posttranslational modifications of P-TEFb regulate transcription elongation.Control of HIV latency by epigenetic and non-epigenetic mechanisms.Making a Short Story Long: Regulation of P-TEFb and HIV-1 Transcriptional Elongation in CD4+ T Lymphocytes and Macrophages.RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP.Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.Solution structure of the 5'-terminal hairpin of the 7SK small nuclear RNA.MORC3, a Component of PML Nuclear Bodies, Has a Role in Restricting Herpes Simplex Virus 1 and Human Cytomegalovirus.Tissue- and context-dependent modulation of hormonal sensitivity of glucocorticoid-responsive genes by hexamethylene bisacetamide-inducible protein 1Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb.Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb.Evolution of 7SK RNA and its protein partners in metazoa.
P2860
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P2860
Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@ast
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@en
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@nl
type
label
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@ast
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@en
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@nl
prefLabel
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@ast
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@en
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@nl
P2093
P2860
P3181
P356
P1476
Oligomerization of HEXIM1 via ...... rects the inhibition of P-TEFb
@en
P2093
B Matija Peterlin
Dalibor Blazek
Irena Oven
Jiri Kohoutek
Matjaz Barboric
P2860
P304
P3181
P356
10.1093/NAR/GKI997
P407
P577
2005-12-23T00:00:00Z