Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

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Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2).

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Q47279133-53AB62A6-2034-4D63-B647-34969ADC77C5

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Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

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http://www.wikidata.org/entity/Q42325001

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

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Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

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Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

@en

Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

@nl

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Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

@en

Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

@nl

P1476

Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

@en

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Giannino Del Sal

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Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy

Mutant p53: One, No One, and One Hundred Thousand

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Modulation of oxidative stress as an anticancer strategy

Targeting triple negative breast cancer: is p53 the answer?

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism.

The Dual Roles of NRF2 in Cancer.

Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species.

Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.

Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.

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e1217967

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scholarly article

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10.1080/23723556.2016.1217967

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Kamil Lisek

Dawid Walerych

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2016-09-02T00:00:00Z

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28197530

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5286961

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Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

about

P2860

P2860

Mutant p53-Nrf2 axis regulates the proteasome machinery in cancer

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932