about
Mutant p53: One, No One, and One Hundred ThousandHsp90 regulates the activity of wild type p53 under physiological and elevated temperaturesCooperation of p53 mutations with other oncogenic alterations in cancer.Targeting mutant p53 in cancer: a long road to precision therapy.The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin.Hsp90 chaperones wild-type p53 tumor suppressor protein.Identification of a HLA-A*0201-restricted immunogenic epitope from the universal tumor antigen DEPDC1.Mutant p53-Nrf2 axis regulates the proteasome machinery in cancerMulti-omics reveals global effects of mutant p53 gain-of-function.Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.Psc3 cohesin of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms.Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.Mutant p53 tunes the NRF2-dependent antioxidant response to support survival of cancer cells.Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanismHsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Dawid Walerych
@ast
Dawid Walerych
@en
Dawid Walerych
@es
Dawid Walerych
@nl
Dawid Walerych
@sl
type
label
Dawid Walerych
@ast
Dawid Walerych
@en
Dawid Walerych
@es
Dawid Walerych
@nl
Dawid Walerych
@sl
prefLabel
Dawid Walerych
@ast
Dawid Walerych
@en
Dawid Walerych
@es
Dawid Walerych
@nl
Dawid Walerych
@sl
P106
P108
P21
P31
P496
0000-0002-8440-1375