BORC, a multisubunit complex that regulates lysosome positioning.
about
Arf-like GTPase Arl8: Moving from the periphery to the center of lysosomal biologyA lysosome-centered view of nutrient homeostasisBLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling EndosomesBLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriersTSSC1 is novel component of the endosomal retrieval machinerySorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone.Bivalent Motif-Ear Interactions Mediate the Association of the Accessory Protein Tepsin with the AP-4 Adaptor Complex.Regulation of synaptic activity by snapin-mediated endolysosomal transport and sorting.mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells.The awesome lysosome.The light chains of kinesin-1 are autoinhibited.A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repairThe lysosome as a command-and-control center for cellular metabolism.PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.RNF167 targets Arl8B for degradation to regulate lysosome positioning and endocytic trafficking.Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes.Overexpression of caveolin-1 reduces Taxol resistance in human osteosarcoma cells by attenuating PI3K-Akt-JNK dependent autophagy.Mechanisms and functions of lysosome positioning.Storage pool diseases illuminate platelet dense granule biogenesis.Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II.Moving and positioning the endolysosomal system.The big and intricate dreams of little organelles: Embracing complexity in the study of membrane traffic.The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivoBLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development.Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain.Homozygous Mutations in TBC1D23 Lead to a Non-degenerative Form of Pontocerebellar Hypoplasia.Folliculin - A tumor suppressor at the intersection of metabolic signaling and membrane traffic.Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.Plasma membrane repairs by small GTPase Rab3a.BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon.SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain.BORC coordinates encounter and fusion of lysosomes with autophagosomes.TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.Impaired p65 degradation by decreased chaperone-mediated autophagy activity facilitates epithelial-to-mesenchymal transition.Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion.Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology.PtdIns3P controls mTORC1 signaling through lysosomal positioning.A Ragulator-BORC interaction controls lysosome positioning in response to amino acid availability.
P2860
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P2860
BORC, a multisubunit complex that regulates lysosome positioning.
description
2015 nî lūn-bûn
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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2015 թվականի ապրիլին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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BORC, a multisubunit complex that regulates lysosome positioning
@nl
BORC, a multisubunit complex that regulates lysosome positioning.
@ast
BORC, a multisubunit complex that regulates lysosome positioning.
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BORC, a multisubunit complex that regulates lysosome positioning
@nl
BORC, a multisubunit complex that regulates lysosome positioning.
@ast
BORC, a multisubunit complex that regulates lysosome positioning.
@en
prefLabel
BORC, a multisubunit complex that regulates lysosome positioning
@nl
BORC, a multisubunit complex that regulates lysosome positioning.
@ast
BORC, a multisubunit complex that regulates lysosome positioning.
@en
P2093
P2860
P921
P3181
P1433
P1476
BORC, a multisubunit complex that regulates lysosome positioning
@en
P2093
Christina Schindler
Michal Jarnik
Peter Backlund
P2860
P304
P3181
P356
10.1016/J.DEVCEL.2015.02.011
P407
P577
2015-04-01T00:00:00Z