BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules
about
The Hermansky-Pudlak syndrome 1 (HPS1) and HPS4 proteins are components of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organellesZinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomesA germline mutation in BLOC1S3/reduced pigmentation causes a novel variant of Hermansky-Pudlak syndrome (HPS8)Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4Family-wide characterization of the DENN domain Rab GDP-GTP exchange factorsCharacterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organellesThe dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowthReinvestigation of the dysbindin subunit of BLOC-1 (biogenesis of lysosome-related organelles complex-1) as a dystrobrevin-binding proteinHermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)Melanocyte-specific proteins are aberrantly trafficked in melanocytes of Hermansky-Pudlak syndrome-type 3Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4BORC, a multisubunit complex that regulates lysosome positioning.Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain.SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosisYeast homologues of three BLOC-1 subunits highlight KxDL proteins as conserved interactors of BLOC-1.Arf-like GTPase Arl8: Moving from the periphery to the center of lysosomal biologyDysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomesFunctional characterization of Wiskott-Aldrich syndrome protein and scar homolog (WASH), a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 (BLOS2) and gamma-tubulinMammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeletonMutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 miceThe BLOS1-interacting protein KXD1 is involved in the biogenesis of lysosome-related organellesHermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampusBLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomesCharacterization of rat BLOS2/Ceap, a putative yeast She3 homolog, as interaction partner of apoptosis antagonizing transcription factor/Che-1Role of dysbindin in dopamine receptor trafficking and cortical GABA functionRoles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesiclesDysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade.Haploinsufficiency of two histone modifier genes on 6p22.3, ATXN1 and JARID2, is associated with intellectual disability.BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling EndosomesDysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner.Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.Dysbindin-1C is required for the survival of hilar mossy cells and the maturation of adult newborn neurons in dentate gyrus.C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules.Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function.Dysbindin-associated proteome in the p2 synaptosome fraction of mouse brainRETRACTED: A BLOC-1 mutation screen reveals that PLDN is mutated in Hermansky-Pudlak Syndrome type 9.
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P2860
BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@ast
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@en
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@en-gb
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@nl
type
label
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@ast
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@en
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@en-gb
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@nl
prefLabel
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@ast
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@en
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@en-gb
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@nl
P2093
P2860
P3181
P356
P1476
BLOC-1, a novel complex contai ...... es and platelet-dense granules
@en
P2093
Esteban C Dell'Angelica
Marta Starcevic
Rashi Gautam
P2860
P304
P3181
P356
10.1074/JBC.M204011200
P407
P577
2002-08-02T00:00:00Z