Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).
about
BORC, a multisubunit complex that regulates lysosome positioning.The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3.The BLOS1-interacting protein KXD1 is involved in the biogenesis of lysosome-related organellesChemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling EndosomesBLOC-1 deficiency causes alterations in amino acid profile and in phospholipid and adenosine metabolism in the postnatal mouse hippocampus.Biogenesis of lysosome-related organelles complex-1 subunit 1 (BLOS1) interacts with sorting nexin 2 and the endosomal sorting complex required for transport-I (ESCRT-I) component TSG101 to mediate the sorting of epidermal growth factor receptor intC. elegans BLOC-1 functions in trafficking to lysosome-related gut granules.Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.Regulation of synaptic activity by snapin-mediated endolysosomal transport and sorting.Identification of a Rab GTPase-activating protein cascade that controls recycling of the Rab5 GTPase Vps21 from the vacuole.Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.A BLOC-1 mutation screen reveals a novel BLOC1S3 mutation in Hermansky-Pudlak Syndrome type 8Lysosome-related organelles: unusual compartments become mainstream.Hypopigmentation in Hermansky-Pudlak syndrome.The role of the cytoskeleton and molecular motors in endosomal dynamics.The BLOC-1 Subunit Pallidin Facilitates Activity-Dependent Synaptic Vesicle Recycling.Storage pool diseases illuminate platelet dense granule biogenesis.Pallidin protein in neurodevelopment and its relation to the pathogenesis of schizophrenia.Illuminating the dark side of recycling endosomes.Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.Recognition deficits in mice carrying mutations of genes encoding BLOC-1 subunits pallidin or dysbindin.Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.Dynamic of contribution of UBPy-sorted cargo to acrosome biogenesis: effects of its derailment in a mouse model of globozoospermia, the infertile Vps54 (L967Q) mutant.The β-alanyl-monoamine synthase ebony is regulated by schizophrenia susceptibility gene dysbindin in Drosophila.
P2860
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P248
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P2860
Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1)
@nl
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@ast
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@en
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@en-gb
type
label
Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1)
@nl
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@ast
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@en
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@en-gb
prefLabel
Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1)
@nl
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@ast
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@en
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@en-gb
P2093
P2860
P921
P356
P1476
Assembly and architecture of b ...... organelles complex-1 (BLOC-1).
@en
P2093
Alasdair C Steven
Christina Schindler
Daniel Nemecek
Hyung Ho Lee
James H Hurley
Juan S Bonifacino
Rodolfo Ghirlando
William J Smith
P2860
P304
P356
10.1074/JBC.M111.325746
P407
P577
2011-12-27T00:00:00Z