Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
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Epigenetic Modulators of Monocytic Function: Implication for Steady State and Disease in the CNSNeuroinflammation in motor neuron diseaseRNA-Binding Proteins in the Regulation of miRNA Activity: A Focus on Neuronal FunctionsFrom the Cajal alumni Achúcarro and Río-Hortega to the rediscovery of never-resting microgliaGlucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell deathDepletion of microglia and inhibition of exosome synthesis halt tau propagation.RNA-targeted Therapeutics for ALSIn vivo inhibition of miR-155 significantly alters post-stroke inflammatory responseRNA metabolism in neurodegenerative disease.Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis.Evidence for an early innate immune response in the motor cortex of ALS.Up-regulation of neural and cell cycle-related microRNAs in brain of amyotrophic lateral sclerosis mice at late disease stageA Comprehensive Profile of ChIP-Seq-Based Olig2 Target Genes in Motor Neuron Progenitor Cells Suggests the Possible Involvement of Olig2 in the Pathogenesis of Amyotrophic Lateral Sclerosis.miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic DysfunctionCharacterisation of Immune and Neuroinflammatory Changes Associated with Chemotherapy-Induced Peripheral Neuropathy.TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease.miR-155 Deletion in Female Mice Prevents Diet-Induced ObesitymiR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair.Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model.M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b.Exosome-Based Delivery of miR-124 in a Huntington's Disease Model.Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury.Inflammation-induced miRNA-155 inhibits self-renewal of neural stem cells via suppression of CCAAT/enhancer binding protein β (C/EBPβ) expression.MicroRNAs: Roles in Regulating Neuroinflammation.Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease.Microglia Versus Myeloid Cell Nomenclature during Brain InflammationA retrospective review of the progress in amyotrophic lateral sclerosis drug discovery over the last decade and a look at the latest strategies.Transcriptional control of microglia phenotypes in health and disease.Central nervous system myeloid cells as drug targets: current status and translational challenges.MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.Manipulating MicroRNAs in Murine Models: Targeting the Multi-Targeting in EpilepsyExosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype.Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes.The microglial ATP-gated ion channel P2X7 as a CNS drug target.Role of Microglia in Neurological Disorders and Their Potentials as a Therapeutic Target.Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases.Activation of microglia by retroviral infection correlates with transient clearance of prions from the brain but does not change incubation time.Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect.MicroRNA-125b regulates microglia activation and motor neuron death in ALS.
P2860
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P2860
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
@nl
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
@ast
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
@en
type
label
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
@nl
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
@ast
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
@en
prefLabel
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
@nl
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
@ast
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
@en
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
@en
P2093
Anna M Krichevsky
Camille E Doykan
David J Greco
Gopal Murugaiyan
James Berry
Matthew P Frosch
Oleg Butovsky
Olga Kiner
Pauline M Wu
Rachid El Fatimy
P2860
P3181
P356
10.1002/ANA.24304
P407
P50
P577
2014-11-27T00:00:00Z