Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells
about
Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signalingAntiviral actions of interferonsSequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genesImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionRole of Autophagy and Apoptosis in the Postinfluenza Bacterial PneumoniaInfluenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKRNegative regulation of cytoplasmic RNA-mediated antiviral signalingThe Influenza A Virus Protein NS1 Displays Structural PolymorphismInfluenza virus NS1 protein counteracts PKR-mediated inhibition of replication.A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in miceSH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation.Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenzaGlobal host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.Multiple anti-interferon actions of the influenza A virus NS1 proteinThe NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathwaysGenetic analysis of influenza virus NS1 gene: a temperature-sensitive mutant shows defective formation of virus particles.The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIVDouble-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor.Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathwayThe role of alpha/beta and gamma interferons in development of immunity to influenza A virus in miceActivation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 proteinMutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs.Influenza virus ns1 protein induces apoptosis in cultured cells.Identification of Novel and Efficacious Chemical Compounds that Disturb Influenza A Virus Entry in vitroProtein synthesis shut-off induced by influenza virus infection is independent of PKR activityTranslational control of viral gene expression in eukaryotesFull genome comparison and characterization of avian H10 viruses with different pathogenicity in Mink (Mustela vison) reveals genetic and functional differences in the non-structural gene.Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response.Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: outcome with influenza A virus is unique.Molecular pathways in virus-induced cytokine production.Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble.Molecular mechanisms of viral inhibitors of RIG-I-like receptors.Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.Structure-based design of NS2 mutants for attenuated influenza A virus vaccinesDifferences in the ability to suppress interferon β production between allele A and allele B NS1 proteins from H10 influenza A viruses.Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.A comprehensive map of the influenza A virus replication cycleEffect of human activated NRAS on replication of delNS1 H5N1 influenza virus in MDCK cells.Replication of herpes simplex virus 1 depends on the gamma 134.5 functions that facilitate virus response to interferon and egress in the different stages of productive infection.
P2860
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P2860
Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mutant influenza viruses with ...... ation of PKR in infected cells
@ast
Mutant influenza viruses with ...... ation of PKR in infected cells
@en
Mutant influenza viruses with ...... ation of PKR in infected cells
@nl
type
label
Mutant influenza viruses with ...... ation of PKR in infected cells
@ast
Mutant influenza viruses with ...... ation of PKR in infected cells
@en
Mutant influenza viruses with ...... ation of PKR in infected cells
@nl
prefLabel
Mutant influenza viruses with ...... ation of PKR in infected cells
@ast
Mutant influenza viruses with ...... ation of PKR in infected cells
@en
Mutant influenza viruses with ...... ation of PKR in infected cells
@nl
P2093
P2860
P3181
P1433
P1476
Mutant influenza viruses with ...... ation of PKR in infected cells
@en
P2093
P2860
P304
P3181
P577
1999-03-01T00:00:00Z