The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
about
Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4Nuclear targeting of transforming growth factor-beta-activated Smad complexesThe transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteinsThe mechanism of nuclear export of Smad3 involves exportin 4 and RanSmad3 allostery links TGF-beta receptor kinase activation to transcriptional controlStoichiometry of active smad-transcription factor complexes on DNASmad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNThe chemical biology of protein phosphorylationDual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodelingSignal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their CrosstalksRegulation of TGF-β signal transduction by mono- and deubiquitylation of Smadsp53 target gene SMAR1 is dysregulated in breast cancer: its role in cancer cell migration and invasionCrystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivationCrystal structure of the MH2 domain of Drosophila MadTwo short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoNNovel SMAD4 mutation causing Myhre syndromeDifferent Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif.BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formationMinireview: Activin Signaling in Gonadotropes: What Does the FOX say… to the SMAD?Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasionPhysicochemical mechanisms of protein regulation by phosphorylation.Bone morphogenetic proteins and their antagonists: current and emerging clinical uses.Smad signalling in the ovaryThe Local Control of the Pituitary by Activin Signaling and Modulation.Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter.A restricted spectrum of mutations in the SMAD4 tumor-suppressor gene underlies Myhre syndrome.Small-molecule-mediated rescue of protein function by an inducible proteolytic shuntAssociation of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer.The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisRotavirus NSP1 mediates degradation of interferon regulatory factors through targeting of the dimerization domainSmad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2.Monomeric and dimeric models of ERK2 in conjunction with studies on cellular localization, nuclear translocation, and in vitro analysis.SMAD4 mutations causing Myhre syndrome result in disorganization of extracellular matrix improved by losartanBMP/Smad signaling and embryonic cerebellum development: stem cell specification and heterogeneity of anterior rhombic lip.Transcriptional Control by the SMADs.Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads.The changing role of TGFβ in healthy, ageing and osteoarthritic joints.Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.CREBZF, a novel Smad8-binding protein.
P2860
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P2860
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@ast
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@en
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@nl
type
label
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@ast
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@en
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@nl
prefLabel
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@ast
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@en
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@nl
P2093
P3181
P356
P1476
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
@en
P2093
P2888
P304
P3181
P356
10.1038/84995
P577
2001-03-01T00:00:00Z
P5875
P6179
1008671908