X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
about
Crystal structures of 70S ribosomes bound to release factors RF1, RF2 and RF3Investigation of the roles of catalytic residues in serotonin N-acetyltransferaseX-ray structure of a serine protease acyl-enzyme complex at 0.95-A resolutionTrypsin revisited: crystallography AT (SUB) atomic resolution and quantum chemistry revealing details of catalysisCapture of an intermediate in the catalytic cycle of L-aspartate- -semialdehyde dehydrogenaseCrystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formationAn unusual helix-turn-helix protease inhibitory motif in a novel trypsin inhibitor from seeds of Veronica (Veronica hederifolia L.)Testing Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion HoleCrystal structure of a translation termination complex formed with release factor RF2Structural and biochemical analyses reveal how ornithine acetyl transferase binds acidic and basic amino acid substratesStructural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolaseCrystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2Atomic resolution structure of a lysine-specific endoproteinase from Lysobacter enzymogenes suggests a hydroxyl group bound to the oxyanion holeTrans-editing of mischarged tRNAs.Mechanism of Orlistat Hydrolysis by the Thioesterase of Human Fatty Acid Synthase.The structural basis of a conserved P2 threonine in canonical serine proteinase inhibitors.Vibrational Stark Effects of Carbonyl Probes Applied to Reinterpret IR and Raman Data for Enzyme Inhibitors in Terms of Electric Fields at the Active SiteDiscrimination between distant homologs and structural analogs: lessons from manually constructed, reliable data setsA papain-like enzyme at work: native and acyl-enzyme intermediate structures in phytochelatin synthesis.The enzymes of β-lactam biosynthesis.Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates.An inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line.Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: Exploiting the "glass transition" in protein dynamics.The protein structures that shape caspase activity, specificity, activation and inhibition.Energy Landscape Topography Reveals the Underlying Link Between Binding Specificity and Activity of EnzymesStructural aspects of translation termination on the ribosome.Atomic resolution structure of serine protease proteinase K at ambient temperature.Observation of a tetrahedral reaction intermediate in the HIV-1 protease-substrate complex.Enzyme-specific activation versus leaving group ability.Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases.Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics.Structural basis of ribosomal peptide macrocyclization in plants.Structural basis for the catalytic mechanism and α-ketoglutarate cooperativity of glutamate dehydrogenase.Time-resolved structural studies of protein reaction dynamics: a smorgasbord of X-ray approaches.Structural Analyses on Intermediates in Serine Protease CatalysisTherapeutic applications of serine protease inhibitors
P2860
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P2860
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@ast
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@en
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@nl
type
label
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@ast
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@en
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@nl
prefLabel
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@ast
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@en
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@nl
P2093
P356
P1476
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate
@en
P2093
P304
P356
10.1038/90401
P577
2001-08-01T00:00:00Z