Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases.

Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases.

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http://www.wikidata.org/entity/Q43956367
Trypsin revisited: crystallography AT (SUB) atomic resolution and quantum chemistry revealing details of catalysisCrystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formationConformational flexibility in the catalytic triad revealed by the high-resolution crystal structure ofStreptomyces erythraeustrypsin in an unliganded stateCrystal structure of 6-guanidinohexanoyl trypsin near the optimum pH reveals the acyl-enzyme intermediate to be deacylatedalpha-lytic protease can exist in two separately stable conformations with different His57 mobilities and catalytic activities.The structural basis of a conserved P2 threonine in canonical serine proteinase inhibitors.Catalytic reaction mechanism of acetylcholinesterase determined by Born-Oppenheimer ab initio QM/MM molecular dynamics simulations.Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates.The protein structures that shape caspase activity, specificity, activation and inhibition.Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme.Molecular dynamics simulations on pars intercerebralis major peptide-C (PMP-C) reveal the role of glycosylation and disulfide bonds in its enhanced structural stability and function.(William) Graham RichardsStructural Analyses on Intermediates in Serine Protease Catalysis
P2860

Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases.

Item
http://www.wikidata.org/entity/Q43956367
description
2002 nî lūn-bûn
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2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
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name
Molecular dynamics simulations ...... tion step of serine proteases.
@en
Molecular dynamics simulations ...... tion step of serine proteases.
@nl
type
label
Molecular dynamics simulations ...... tion step of serine proteases.
@en
Molecular dynamics simulations ...... tion step of serine proteases.
@nl
prefLabel
Molecular dynamics simulations ...... tion step of serine proteases.
@en
Molecular dynamics simulations ...... tion step of serine proteases.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Molecular dynamics simulations ...... tion step of serine proteases.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698