Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
about
Hierarchical docking of databases of multiple ligand conformationsThree decades of beta-lactamase inhibitorsStructure-based discovery of opioid analgesics with reduced side effects.Rescoring Docking Hit Lists for Model Cavity Sites: Predictions and Experimental TestingComprehensive Mechanistic Analysis of Hits from High-Throughput and Docking Screens against β-LactamaseMolecular docking and ligand specificity in fragment-based inhibitor discoveryDocking for fragment inhibitors of AmpC -lactamaseDesign, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase InhibitorsAnopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellentsIncreasing Chemical Space Coverage by Combining Empirical and Computational Fragment ScreensTargeting Class A and C Serine β-Lactamases with a Broad-Spectrum Boronic Acid DerivativeAutomated docking screens: a feasibility studyBiochemical characterization of CTX-M-15 from Enterobacter cloacae and designing a novel non-β-lactam-β-lactamase inhibitorCovalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatasesBenchmarking sets for molecular dockingDecoys for dockingVariety of antiprion compounds discovered through an in silico screen based on cellular-form prion protein structure: Correlation between antiprion activity and binding affinity.Docking screens: right for the right reasons?Docking Screens for Novel Ligands Conferring New Biology.Identification of residues critical for catalysis in a class C beta-lactamase by combinatorial scanning mutagenesis.Virtual screening of chemical libraries.Here be dragons: docking and screening in an uncharted region of chemical spaceNew disturbing trend in antimicrobial resistance of gram-negative pathogensStructure-based discovery of A2A adenosine receptor ligands.SiMMap: a web server for inferring site-moiety map to recognize interaction preferences between protein pockets and compound moieties.Fluorescent TEM-1 β-lactamase with wild-type activity as a rapid drug sensor for in vitro drug screening.Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4Structure-based discovery of antagonists of nuclear receptor LRH-1.Anesthetic-like modulation of receptor function by surfactants: a test of the interfacial theory of anesthesiaA hypothesis on the origin and evolution of the response to inhaled anestheticsFragment-based inhibitor discovery against β-lactamaseSearch for non-lactam inhibitors of mtb β-lactamase led to its open shape in apo state: new concept for antibiotic designStructure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell cultureAutomating crystallographic structure solution and refinement of protein-ligand complexes.Directory of useful decoys, enhanced (DUD-E): better ligands and decoys for better benchmarkingOn 3LEZ, a deep-sea halophilic protein with in vitro class-a β-lactamase activity: molecular-dynamics, docking, and reactivity simulations.Pharmacophore modeling using site-identification by ligand competitive saturation (SILCS) with multiple probe molecules.Structure-based inhibitor discovery against adenylyl cyclase toxins from pathogenic bacteria that cause anthrax and whooping cough.Discovery of new GPCR ligands to illuminate new biology.
P2860
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P2860
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@ast
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@en
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@nl
type
label
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@ast
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@en
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@nl
prefLabel
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@ast
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@en
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@nl
P2093
P1433
P1476
Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase
@en
P2093
Brian K Shoichet
Federica Morandi
Rachel A Powers
P304
P356
10.1016/S0969-2126(02)00799-2
P577
2002-07-01T00:00:00Z