SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. - Wikidata - awgldk - TriplyDB

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

http://www.wikidata.org/entity/Q34289658

about

Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids The circadian clock in cancer development and therapy Hepatocyte nuclear factor-4alpha contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthase MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.Gene expression profiling and network analysis reveals lipid and steroid metabolism to be the most favored by TNFalpha in HepG2 cells.Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis.Role of hepatocyte nuclear factor 4α in controlling copper-responsive transcription.Nutrient sensor-mediated programmed nonalcoholic fatty liver disease in low birthweight offspring Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARα and HNF4α in the Liver Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1.Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signals Cholesterol dependent downregulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences.Adiponectin regulates expression of hepatic genes critical for glucose and lipid metabolism.Chronic Hyperinsulinemia Causes Selective Insulin Resistance and Down-regulates Uncoupling Protein 3 (UCP3) through the Activation of Sterol Regulatory Element-binding Protein (SREBP)-1 Transcription Factor in the Mouse Heart Transcriptional regulation by insulin: from the receptor to the gene.MicroRNA 33 regulates glucose metabolism.Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis.SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding.Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs.L-FABP directly interacts with PPARalpha in cultured primary hepatocytes.SREBPs: protein interaction and SREBPs.A novel pathway of insulin sensitivity in chromogranin A null mice: a crucial role for pancreastatin in glucose homeostasis.The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer's Disease.Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver.Role of Sirt1 during the ageing process: relevance to protection of synapses in the brain.Signaling pathway cross talk in Alzheimer's disease Relevance of microRNA in metabolic diseases.Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays.Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice.Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection.Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.Identification of DNA regions and a set of transcriptional regulatory factors involved in transcriptional regulation of several human liver-enriched transcription factor genes.Nuclear receptors in the mosquito Aedes aegypti: annotation, hormonal regulation and expression profiling.

P2860

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P2860

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

http://www.wikidata.org/entity/Q34289658

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2004 թվականի հունվարին հրատարակված գիտական հոդված

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

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name

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@ast

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@en

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

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type

label

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@ast

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@en

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@nl

prefLabel

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@ast

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@en

SREBP-1 interacts with hepatoc ...... s hepatic gluconeogenic genes.

@nl

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P1433

Journal of Biological Chemistry

P1476

SREBP-1 interacts with hepatoc ...... ss hepatic gluconeogenic genes

@en

P2093

Akimitsu Takahashi

http://www.w3.org/2001/XMLSchema#string

Hideo Toyoshima

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Hiroaki Suzuki

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Hitoshi Shimano

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Masanori Nakakuki

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Nobuhiro Yamada

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Ryuichiro Sato

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Takashi Matsuzaka

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Takashi Yamamoto

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Tomohiro Ide

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P2860

Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes

Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

Organization and partial sequence of the hepatocyte nuclear factor-4 alpha/MODY1 gene and identification of a missense mutation, R127W, in a Japanese family with MODY

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

P304

12027-12035

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scholarly article

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10.1074/JBC.M310333200

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P407

P433

13

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P478

279

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P577

2004-01-13T00:00:00Z

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14722127

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