about
The development of drugs for treatment of sleeping sickness: a historical reviewNovel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1Novel amidines and analogues as promising agents against intracellular parasites: a systematic reviewIn and out of the minor groove: interaction of an AT-rich DNA with the drug CD27In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infectionCombined treatment of heterocyclic analogues and benznidazole upon Trypanosoma cruzi in vivoScreening of Potential anti-Trypanosoma cruzi Candidates: In Vitro and In Vivo Studies.Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatmentPafuramidine for Pneumocystis jiroveci pneumonia in HIV-infected individuals.Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents.SYNTHESIS OF NOVEL BITHIOPHENE-SUBSTITUTED HETEROCYCLES BEARING CARBONITRILE GROUPS.A new nonpolar N-hydroxy imidazoline lead compound with improved activity in a murine model of late-stage Trypanosoma brucei brucei infection is not cross-resistant with diamidines.Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones.Molecular determinants of pentamidine-induced hERG trafficking inhibition.Novel 4-substituted phenyl-2,2'-bichalcophenes and aza-analogs as antibacterial agents: a structural activity relationship.Antiparasitic compounds that target DNA.Synthesis and SAR of alkanediamide-linked bisbenzamidines with anti-trypanosomal and anti-pneumocystis activity.Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice.New treatment option for second-stage African sleeping sickness: in vitro and in vivo efficacy of aza analogs of DB289In vivo investigations of selected diamidine compounds against Trypanosoma evansi using a mouse model.Drug target identification in protozoan parasites.Activity of diimidazoline amides against African trypanosomiasis.Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues.Biological, ultrastructural effect and subcellular localization of aromatic diamidines in Trypanosoma cruzi.Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles.Effects of aqueous extracts of Acacia albida stem bark on Wistar albino rats infected with Trypanosoma evansi.Electrocardiographic findings in acutely and chronically T. cruzi-infected mice treated by a phenyl-substituted analogue of furamidine DB569.Cellular effects of reversed amidines on Trypanosoma cruzi.In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi.Potential of bisbenzimidazole-analogs toward metronidazole-resistant Trichomonas vaginalis isolates.The adaptive potential of a survival artist: characterization of the in vitro interactions of Toxoplasma gondii tachyzoites with di-cationic compounds in human fibroblast cell cultures.Synthesis, DNA affinity, and antimicrobial activity of 4-substituted phenyl-2,2′-bichalcophenes and aza-analogues
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Aromatic diamidines as antiparasitic agents.
@ast
Aromatic diamidines as antiparasitic agents.
@en
type
label
Aromatic diamidines as antiparasitic agents.
@ast
Aromatic diamidines as antiparasitic agents.
@en
prefLabel
Aromatic diamidines as antiparasitic agents.
@ast
Aromatic diamidines as antiparasitic agents.
@en
P2093
P2860
P1476
Aromatic diamidines as antiparasitic agents.
@en
P2093
De Souza EM
Stephens CE
P2860
P304
P356
10.1517/13543784.14.8.957
P407
P577
2005-08-01T00:00:00Z