Mimicking natural evolution in vitro: An N-acetylneuraminate lyase mutant with an increased dihydrodipicolinate synthase activity
about
Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolasesDiscovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †Structure of anEscherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 Å resolutionStructural Insights into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed EvolutionIdentification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysisReaction Mechanism of N -Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and MutagenesisCharacterization of a novel N-acetylneuraminic acid lyase favoring N-acetylneuraminic acid synthesisLaboratory evolution of one disulfide isomerase to resemble anotherLaboratory-directed protein evolutionSaturation mutagenesis of Asn152 reveals a substrate selectivity switch in P99 cephalosporinasePatterns of evolutionary conservation of essential genes correlate with their compensability4-Hydroxy-2-oxoglutarate aldolase inactivity in primary hyperoxaluria type 3 and glyoxylate reductase inhibitionDirected evolution of aldolases for exploitation in synthetic organic chemistry2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells.Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities.Enzyme (re)design: lessons from natural evolution and computation.Computational enzyme design.Molecular characterization of a novel N-acetylneuraminate lyase from Lactobacillus plantarum WCFS1.Structural insights into conserved L-arabinose metabolic enzymes reveal the substrate binding site of a thermophilic L-arabinose isomerase.Horizontally acquired DAP pathway as a unit of self-regulation.Molecular evolution of an oligomeric biocatalyst functioning in lysine biosynthesis.Stable carbon isotope fractionation during degradation of dichloromethane by methylotrophic bacteria.
P2860
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P2860
Mimicking natural evolution in vitro: An N-acetylneuraminate lyase mutant with an increased dihydrodipicolinate synthase activity
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mimicking natural evolution in ...... dipicolinate synthase activity
@ast
Mimicking natural evolution in ...... dipicolinate synthase activity
@en
Mimicking natural evolution in ...... dipicolinate synthase activity
@nl
type
label
Mimicking natural evolution in ...... dipicolinate synthase activity
@ast
Mimicking natural evolution in ...... dipicolinate synthase activity
@en
Mimicking natural evolution in ...... dipicolinate synthase activity
@nl
prefLabel
Mimicking natural evolution in ...... dipicolinate synthase activity
@ast
Mimicking natural evolution in ...... dipicolinate synthase activity
@en
Mimicking natural evolution in ...... dipicolinate synthase activity
@nl
P2860
P356
P1476
Mimicking natural evolution in ...... dipicolinate synthase activity
@en
P2093
Sebastian Mayer
P2860
P304
P356
10.1073/PNAS.0531477100
P407
P577
2003-05-13T00:00:00Z