Reaction Mechanism of N -Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis
about
Characterization of a novel N-acetylneuraminic acid lyase favoring N-acetylneuraminic acid synthesisFirst functional and mutational analysis of group 3 N-acetylneuraminate lyases from Lactobacillus antri and Lactobacillus sakei 23KExtending enzyme molecular recognition with an expanded amino acid alphabet.Computational tools for the evaluation of laboratory-engineered biocatalysts.Evaluation of fluoropyruvate as nucleophile in reactions catalysed by N-acetyl neuraminic acid lyase variants: scope, limitations and stereoselectivity.Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.Multiscale analysis of enantioselectivity in enzyme-catalysed 'lethal synthesis' using projector-based embedding.Direct synthesis of C-glycosides from unprotected 2-N-acyl-aldohexoses via aldol condensation–oxa-Michael reactions with unactivated ketonesReactions of pyruvates: organocatalytic synthesis of functionalized dihydropyrans in one pot and further transformations to functionalized carbocycles and heterocycles
P2860
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P2860
Reaction Mechanism of N -Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@ast
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@en
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@en-gb
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@nl
type
label
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@ast
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@en
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@en-gb
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@nl
prefLabel
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@ast
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@en
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@en-gb
Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@nl
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P2860
P50
P356
P1154
2-s2.0-84899082484
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Reaction Mechanism of N -Acety ...... MM Simulation, and Mutagenesis
@en
P2093
Adam D Daniels
Amanda H Bolt
Chi H Trinh
Simon E V Phillips
P2860
P304
P356
10.1021/CB500067Z
P5530
P577
2014-04-18T00:00:00Z
P5875
P6179
1039942383