Inhibition of class A and class C beta-lactamases by penems: crystallographic structures of a novel 1,4-thiazepine intermediate
about
Three decades of beta-lactamase inhibitorsHydrolysis of third-generation cephalosporins by class C beta-lactamases. Structures of a transition state analog of cefotoxamine in wild-type and extended spectrum enzymesRe-examining the role of Lys67 in class C β-lactamase catalysisStructures of the Michaelis Complex (1.2 Å) and the Covalent Acyl Intermediate (2.0 Å) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis β-Lactamase K73A and E166A Mutants,Ligand-Dependent Disorder of the Loop Observed in Extended-Spectrum SHV-Type -LactamaseStructures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugationβ-Lactamase Inhibition by 7-Alkylidenecephalosporin Sulfones: Allylic Transposition and Formation of an Unprecedented Stabilized Acyl-EnzymeStructure of the extended-spectrum class C β-lactamase ADC-1 fromAcinetobacter baumanniiKinetic and Structural Characterization of the Interaction of 6-Methylidene Penem 2 with the β-Lactamase from Mycobacterium tuberculosisTrapping and characterization of a reaction intermediate in carbapenem hydrolysis by B. cereus metallo-beta-lactamase.The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution.Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition.Inhibition of OXA-1 beta-lactamase by penems.The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems.Classification of Beta-lactamases and penicillin binding proteins using ligand-centric network models.Beta-lactamase inhibitors: evolving compounds for evolving resistance targets.Ligand identification using electron-density map correlationsIn vitro and in vivo activities of novel 6-methylidene penems as beta-lactamase inhibitors.Cyclic Boronates Inhibit All Classes of β-Lactamases.Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance.Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor.Exploring Additional Dimensions of Complexity in Inhibitor Design for Serine β-Lactamases: Mechanistic and Intra- and Inter-molecular Chemistry Approaches.A fluorescein-labeled AmpC β-lactamase allows rapid characterization of β-lactamase inhibitors by real-time fluorescence monitoring of the β-lactamase-inhibitor interactions.
P2860
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P2860
Inhibition of class A and class C beta-lactamases by penems: crystallographic structures of a novel 1,4-thiazepine intermediate
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@ast
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@en
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@nl
type
label
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@ast
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@en
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@nl
prefLabel
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@ast
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@en
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@nl
P2093
P356
P1433
P1476
Inhibition of class A and clas ...... el 1,4-thiazepine intermediate
@en
P2093
Aranapakam M Venkatesan
James R Knox
Michiyoshi Nukaga
Tarek S Mansour
P304
P356
10.1021/BI034986B
P407
P577
2003-11-18T00:00:00Z