Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif
about
A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human CellsCrystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITYThe DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc FingerStructural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1PARP inhibition: PARP1 and beyondSuicidal cross-linking of PARP-1 to AP site intermediates in cells undergoing base excision repair.Influence of PARP-1 polymorphisms in patients after traumatic brain injuryPARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction.Structural dynamics in DNA damage signaling and repairTargeting poly(ADP-ribose) polymerase activity for cancer therapy.Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.Kinetic control of one-pot trans-splicing reactions by using a wild-type and designed split inteinMapping protein surface accessibility via an electron transfer dissociation selectively cleavable hydrazone probeMolecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sitesHuman RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.The Sound of Silence: RNAi in Poly (ADP-Ribose) ResearchFluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage.Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.Conformational activation of poly(ADP-ribose) polymerase-1 upon DNA binding revealed by small-angle X-ray scattering.The role of PARP1 in the DNA damage response and its application in tumor therapy.PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis.Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.Olaparib: a promising PARP inhibitor in ovarian cancer therapy.Structural and biophysical studies of human PARP-1 in complex with damaged DNA.Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors.Therapeutic Targeting of Poly(ADP-Ribose) Polymerase-1 (PARP1) in Cancer: Current Developments, Therapeutic Strategies, and Future Opportunities.Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors.PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNADNA-dependent SUMO modification of PARP-1PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.Double-stranded DNA binding domain of poly(ADP-ribose) polymerase-1 and molecular insight into the regulation of its activity.PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs.A wheat SIMILAR TO RCD-ONE gene enhances seedling growth and abiotic stress resistance by modulating redox homeostasis and maintaining genomic integrity.PARP inhibition attenuates histopathological lesion in ischemia/reperfusion renal mouse model after cold prolonged ischemia.
P2860
Q27318327-19CD1F58-5967-4AC1-81E7-DDD31377B9C4Q27666573-435B2C43-97D2-4A12-A28C-D7AF605515C5Q27666697-2DD1D331-848B-460A-848B-1B5EBF21F84BQ27679074-16169B86-B0B3-4BDD-A5CB-396D88FCD134Q29619617-7C119D42-61A0-4E97-94C7-503EE6D6F5FCQ33698661-3A545224-60F4-42E7-9DA2-60ECB82FC797Q33841650-D74FCFE3-FAB6-4A4D-96A2-7EEF3C565ADBQ33843139-271200C1-3D07-4E56-9EEF-74B4A351D4FDQ33897970-E5AAA0EC-1F32-4C2F-8DA8-1F3CA03DFA5CQ34047906-E67261D3-DB7D-412E-8009-636920073566Q34204660-94432CFC-4848-4EDC-9B1D-B2798B086C85Q34755657-9D8457E1-B7FA-49C3-90E8-590D3343C15DQ35590984-383E67B4-C573-423D-A215-2CBCB773C5C8Q36089904-30B54B11-C55A-4AEB-B3B8-B460CB434C7BQ37235363-F712851B-1C0C-4B04-950E-BAB528A04676Q37499042-0422895A-9321-4492-8E69-7DAF583B7C89Q37508170-579E6D45-9E7D-4EB5-9F21-8DEA0CD1485AQ37522977-564406C5-957A-4540-984C-2DC7AD7B2419Q37644563-86B183B8-0580-4B1A-831C-8F92F8076F3AQ37678007-F9487EAD-02A9-4292-9A6A-A2431B09984EQ38015737-C0E065BF-DE7F-4758-9168-C0FB60D8C644Q38075305-16431029-3472-48A2-A7E6-5E067B3D1339Q38086332-679913E6-D551-4BEE-B81D-5558F542204EQ38101861-9F2A60AF-F797-427F-92BB-D2941E401D36Q38348304-F6FA5CBE-5D01-45EE-A458-46BE7263EFF8Q38596368-B225239C-54D6-4CE6-B8DA-14F3FA2BDD5AQ38683171-F7781321-C818-47B4-BE44-5CB758D38F6DQ38692308-405B952D-8335-4EA0-AEBC-F93F606312FAQ39430828-0AD01D18-AE26-480F-98D5-D8FEB2940BC3Q41898664-F5099B2B-F9A3-4615-B382-543F415E2496Q42095016-AAB1E68F-DF76-452A-8DE8-FAE735BB3F4AQ42632662-C0F65348-B049-421A-955F-1C8F6A539677Q43042008-11AA23E5-977C-4E45-AD4D-775C21DD4EEBQ46944188-8930A84F-FCE7-4F5A-ADFA-F282F0A1E69AQ54471607-882A2B5B-8304-448D-9FF1-C4300C690548
P2860
Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@ast
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@en
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@nl
type
label
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@ast
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@en
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@nl
prefLabel
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@ast
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@en
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@nl
P2093
P3181
P356
P1433
P1476
Domain C of human poly(ADP-rib ...... ains a novel zinc-ribbon motif
@en
P2093
David W Hoffman
Hung-Wen Liu
Zhihua Tao
P304
P3181
P356
10.1021/BI800018A
P407
P577
2008-05-27T00:00:00Z