PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA - Wikidata - awgldk - TriplyDB

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

http://www.wikidata.org/entity/Q39430828

about

Spermatid head elongation with normal nuclear shaping requires ADP-ribosyltransferase PARP11 (ARTD11) in mice Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression Readers of poly(ADP-ribose): designed to be fit for purpose Intracellular Mono-ADP-Ribosylation in Signaling and Disease PARPs and the DNA damage response A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development The role of ADP-ribosylation in regulating DNA interstrand crosslink repair Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation PARP inhibitor treatment in ovarian and breast cancer PARP inhibition: PARP1 and beyond PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.Functional Aspects of PARP1 in DNA Repair and Transcription.Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes.Family-wide analysis of poly(ADP-ribose) polymerase activity The role of ADP-ribosylation in regulating DNA double-strand break repair Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress Poly(ADP-ribosyl)ation acts in the DNA demethylation of mouse primordial germ cells also with DNA damage-independent roles.Affinity-based assays for the identification and quantitative evaluation of noncovalent poly(ADP-ribose)-binding proteins.New PARP targets for cancer therapy NF-κB transcriptional activation by TNFα requires phospholipase C, extracellular signal-regulated kinase 2 and poly(ADP-ribose) polymerase-1 Identification and Functional Characterizations of N-Terminal α-N-Methylation and Phosphorylation of Serine 461 in Human Poly(ADP-ribose) Polymerase 3.Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.A systematic analysis of the PARP protein family identifies new functions critical for cell physiology.Structural Implications for Selective Targeting of PARPs.The Sound of Silence: RNAi in Poly (ADP-Ribose) Research PARP Inhibitors in Reproductive System Cancers: Current Use and Developments.Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics.The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings.Functions of the poly(ADP-ribose) polymerase superfamily in plants.Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes.On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.PARP inhibitors in cancer therapy: an update.Resistance to PARP-Inhibitors in Cancer Therapy.Beyond DNA repair, the immunological role of PARP-1 and its siblings.Drug Monographs: Olaratumab and Rucaparib.The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival.The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair.Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate.Poly(ADP-ribose) regulates post-transcriptional gene regulation in the cytoplasm.

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P2860

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

http://www.wikidata.org/entity/Q39430828

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

2010年學術文章

@zh

2010年學術文章

@zh-hant

name

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

@en

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

@nl

type

label

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

@en

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

@nl

prefLabel

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

@en

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

@nl

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JBC.M109.077834

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Journal of Biological Chemistry

P1476

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA

@en

P2093

Helen E Bryant

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Olga Loseva

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Tobias Karlberg

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P2860

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

Large-scale mapping of human protein-protein interactions by mass spectrometry

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2

Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif

Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3

Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

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scholarly article

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11

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285

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Herwig Schüler

Thomas Helleday

Ann-Sofie Jemth

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2010-01-11T00:00:00Z

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40907532

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20064938

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Poly(ADP-ribose) polymerase family member 3

protein ADP-ribosylase activity

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2832956

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