Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
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From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug designStructure and mechanism ofEscherichia coliglutathionylspermidine amidase belonging to the family of cysteine; histidine-dependent amidohydrolases/peptidasesEnterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug DesignCrystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important ResiduesBroad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93Terpyridine platinum(II) complexes inhibit cysteine proteases by binding to active-site cysteine3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against PicornavirusesInhibition of Enterovirus 71 replication by 7-hydroxyflavone and diisopropyl-flavon7-yl PhosphateThe coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signalingRecent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery.Crystallization and preliminary crystallographic study of Porcine epidemic diarrhea virus main protease in complex with an inhibitorMetal impurities cause false positives in high-throughput screening campaignsHuman coronavirus OC43 3CL protease and the potential of ML188 as a broad-spectrum lead compound: homology modelling and molecular dynamic studies.Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease.Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.Potential Broad Spectrum Inhibitors of the Coronavirus 3CLpro: A Virtual Screening and Structure-Based Drug Design Study.X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus.The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like proteaseMacrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.A Novel Enterovirus 71 (EV71) Virulence Determinant: The 69th Residue of 3C Protease Modulates Pathogenicity.Picornaviral 3C protease inhibitors and the dual 3C protease/coronaviral 3C-like protease inhibitors.Focal adhesion kinase is a component of antiviral RIG-I-like receptor signaling.Structure-based antivirals for emerging and neglected RNA viruses: an emerging field for medicinal chemistry in academia.Coxsackievirus B3 protease 3C: expression, purification, crystallization and preliminary structural insights.Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragmentsChalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV.Inhibitory zinc sites in enzymes.
P2860
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P2860
Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@ast
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@en
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@nl
type
label
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@ast
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@en
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@nl
prefLabel
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@ast
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@en
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@nl
P2093
P2860
P921
P3181
P356
P1476
Structural Basis of Inhibition ...... g and Peptidomimetic Compounds
@en
P2093
Cheng-Chung Lee
Chih-Jung Kuo
Hua-Chien Chen
Min-Feng Hsu
Ming-Chu Hsu
Po-Huang Liang
Shih-Cheng Chang
Shin-Ru Shih
Shu-Jen Chen
Syaulan Yang
P2860
P304
P3181
P356
10.1074/JBC.M807947200
P407
P577
2009-03-20T00:00:00Z