Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues
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Roles of the Picornaviral 3C Proteinase in the Viral Life Cycle and Host CellsRecent developments in antiviral agents against enterovirus 71 infectionCrystal Structure of Enterovirus 71 RNA-Dependent RNA Polymerase Complexed with Its Protein Primer VPg: Implication for a trans Mechanism of VPg UridylylationStructures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivirInhibition of Enterovirus 71 replication by 7-hydroxyflavone and diisopropyl-flavon7-yl PhosphateCrystal structure of 2C helicase from enterovirus 71Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex.Inhibition of enterovirus 71 by adenosine analog NITD008Dominant drug targets suppress the emergence of antiviral resistanceBiochemical characterization of recombinant Enterovirus 71 3C protease with fluorogenic model peptide substrates and development of a biochemical assay.Peptidyl aldehyde NK-1.8k suppresses enterovirus 71 and enterovirus 68 infection by targeting protease 3CEnterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase.Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity.Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responsesStructure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design.Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.Antiviral activities of peptide-based covalent inhibitors of the Enterovirus 71 3C proteaseA Novel Enterovirus 71 (EV71) Virulence Determinant: The 69th Residue of 3C Protease Modulates Pathogenicity.Suramin interacts with the positively charged region surrounding the 5-fold axis of the EV-A71 capsid and inhibits multiple enterovirus A.Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor.Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D.Enteroviral proteases: structure, host interactions and pathogenicity.The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon.RNA-virus proteases counteracting host innate immunity.Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study.Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.Etiology, pathogenesis, antivirals and vaccines of hand, foot, and mouth disease
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P2860
Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues
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2011 nî lūn-bûn
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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
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2011年論文
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2011年論文
@zh-tw
2011年论文
@wuu
name
Crystal Structures of Enterovi ...... talytically Important Residues
@ast
Crystal Structures of Enterovi ...... talytically Important Residues
@en
Crystal Structures of Enterovi ...... talytically Important Residues
@nl
type
label
Crystal Structures of Enterovi ...... talytically Important Residues
@ast
Crystal Structures of Enterovi ...... talytically Important Residues
@en
Crystal Structures of Enterovi ...... talytically Important Residues
@nl
prefLabel
Crystal Structures of Enterovi ...... talytically Important Residues
@ast
Crystal Structures of Enterovi ...... talytically Important Residues
@en
Crystal Structures of Enterovi ...... talytically Important Residues
@nl
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P2860
P3181
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Crystal Structures of Enterovi ...... talytically Important Residues
@en
P2093
Jianwei Wang
Meitian Wang
Tingting Fan
Xiaobo Lei
Zhiqiang Wu
P2860
P304
P3181
P356
10.1128/JVI.05107-11
P50
P577
2011-10-01T00:00:00Z