An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
about
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphomaCell signaling by receptor tyrosine kinasesThe extracellular architecture of adherens junctions revealed by crystal structures of type I cadherinsEph-ephrin signaling in nervous system developmentTargeting the Eph System with Peptides and Peptide ConjugatesMembrane microdomains: from seeing to understandingEph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiationArchitecture of Eph receptor clustersStructure and Binding Mechanism of Vascular Endothelial Cadherin: A Divergent Classical CadherinStructurally encoded intraclass differences in EphA clusters drive distinct cell responsesInsights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5Completing the structural family portrait of the human EphB tyrosine kinase domainsStructural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesionProtein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylationStructural basis of latrophilin-FLRT interactionEphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.Correlative in-resin super-resolution and electron microscopy using standard fluorescent proteins.Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode.Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion.Nanoscale obstacle arrays frustrate transport of EphA2-Ephrin-A1 clusters in cancer cell linesDimerization of Tie2 mediated by its membrane-proximal FNIII domains.Size-based chromatography of signaling clusters in a living cell membraneNormal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implicationsSpatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1.Collagen induces activation of DDR1 through lateral dimer association and phosphorylation between dimersEngineering of monobody conjugates for human EphA2-specific optical imaging.Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations.Cooperativity between trans and cis interactions in cadherin-mediated junction formationEmerging strategies for EphA2 receptor targeting for cancer therapeutics.Activation of transmembrane cell-surface receptors via a common mechanism? The "rotation model".Secreted herpes simplex virus-2 glycoprotein G modifies NGF-TrkA signaling to attract free nerve endings to the site of infection.Unique structure and dynamics of the EphA5 ligand binding domain mediate its binding specificity as revealed by X-ray crystallography, NMR and MD simulationsEphB/ephrinB signaling in cell adhesion and migration.Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligandsCollagen recognition and transmembrane signalling by discoidin domain receptorsEph receptor function is modulated by heterooligomerization of A and B type Eph receptorsDistinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5.Eph/ephrin signaling in epidermal differentiation and diseaseHomotypic receptor-receptor interactions regulating Eph signaling.EphA2 Receptor Unliganded Dimers Suppress EphA2 Pro-tumorigenic Signaling.
P2860
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P2860
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly
@nl
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
@ast
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
@en
type
label
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly
@nl
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
@ast
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
@en
prefLabel
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly
@nl
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
@ast
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
@en
P2093
P2860
P3181
P356
P1476
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
@en
P2093
A Radu Aricescu
Elena Seiradake
Geoff Sutton
Karl Harlos
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1782
P50
P5008
P577
2010-03-14T00:00:00Z
P5875
P6179
1001833172