Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series

Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series

Item
http://www.wikidata.org/entity/Q27667120
Development of o -Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase InhibitorsCompleting the structural family portrait of the human EphB tyrosine kinase domainsDispensing processes impact apparent biological activity as determined by computational and statistical analyses.Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases.Targeting Eph receptors with peptides and small molecules: progress and challenges.The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.Structure-activity relationships and mechanism of action of Eph-ephrin antagonists: interaction of cholanic acid with the EphA2 receptor.Biochemical and biophysical characterization of four EphB kinase domains reveals contrasting thermodynamic, kinetic and inhibition profiles.Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor.Optimization of Highly Kinase Selective Bis-anilino Pyrimidine PAK1 Inhibitors.EphB4: A promising target for upper aerodigestive malignancies.Ligand-Promoted Meta-C-H Amination and Alkynylation.
P2860

Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series

Item
http://www.wikidata.org/entity/Q27667120
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@ast
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@en
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@nl
type
label
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@ast
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@en
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@nl
prefLabel
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@ast
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@en
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Inhibitors of the tyrosine kin ...... n of a benzylic alcohol series
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2011.03.009
P407
P433
P478
P577
P698