Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations
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Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving groupMolecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor regionStructures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site FlexibilityA conformational change in the peripheral anionic site of Torpedo californica acetylcholinesterase induced by a bis-imidazolium oximeMOLE 2.0: advanced approach for analysis of biomacromolecular channelsA wrench in the works of human acetylcholinesterase: soman induced conformational changes revealed by molecular dynamics simulationsGenome organization, phylogenies, expression patterns, and three-dimensional protein models of two acetylcholinesterase genes from the red flour beetle.Crystal structure of snake venom acetylcholinesterase in complex with inhibitory antibody fragment Fab410 bound at the peripheral site: evidence for open and closed states of a back door channel.Enzyme Tunnels and Gates As Relevant Targets in Drug Design.Gates of enzymes.Computational Studies on Acetylcholinesterases.Recent developments in structural studies on acetylcholinesterase.Molecular dynamics simulation study and molecular docking descriptors in structure-based QSAR on acetylcholinesterase (AChE) inhibitors.Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related α/β Hydrolase Fold Proteins or Domains-A Structural Perspective.Interaction between Plectranthus barbatus herbal tea components and acetylcholinesterase: binding and activity studies.A new motif in the N-terminal of acetylcholinesterase triggers amyloid-β aggregation and deposition.Composite aromatic boxes for enzymatic transformations of quaternary ammonium substrates.Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase.Evolutionary origin and status of two insect acetylcholinesterases and their structural conservation and differentiation.Identification of new allosteric sites and modulators of AChE through computational and experimental tools.Molecular Modeling Studies on the Interactions of Aflatoxin B1 and Its Metabolites with Human Acetylcholinesterase. Part II: Interactions with the Catalytic Anionic Site (CAS)
P2860
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P2860
Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Backdoor opening mechanism in ...... molecular dynamics simulations
@ast
Backdoor opening mechanism in ...... molecular dynamics simulations
@en
Backdoor opening mechanism in ...... molecular dynamics simulations
@nl
type
label
Backdoor opening mechanism in ...... molecular dynamics simulations
@ast
Backdoor opening mechanism in ...... molecular dynamics simulations
@en
Backdoor opening mechanism in ...... molecular dynamics simulations
@nl
prefLabel
Backdoor opening mechanism in ...... molecular dynamics simulations
@ast
Backdoor opening mechanism in ...... molecular dynamics simulations
@en
Backdoor opening mechanism in ...... molecular dynamics simulations
@nl
P2093
P2860
P50
P356
P1433
P1476
Backdoor opening mechanism in ...... molecular dynamics simulations
@en
P2093
Benoît Sanson
Hualiang Jiang
P Therese Lang
P2860
P304
P356
10.1002/PRO.661
P577
2011-07-01T00:00:00Z