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Structure-guided simulations illuminate the mechanism of ATP transport through VDAC1Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallographyShoot-and-Trap: Use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallographyThe crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gatingCrystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoximeStructural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylationReaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure AnalysisBackdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulationsMolecular basis for amyloid- polymorphismSampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutionsInhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometryDiscovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitorStructure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agentsSerial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFPDe novo phasing with X-ray laser reveals mosquito larvicide BinAB structure
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
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name
Jacques-Philippe Colletier
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Jacques-Philippe Colletier
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Jacques-Philippe Colletier
@es
Jacques-Philippe Colletier
@nl
Jacques-Philippe Colletier
@sl
type
label
Jacques-Philippe Colletier
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Jacques-Philippe Colletier
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Jacques-Philippe Colletier
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Jacques-Philippe Colletier
@nl
Jacques-Philippe Colletier
@sl
prefLabel
Jacques-Philippe Colletier
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Jacques-Philippe Colletier
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Jacques-Philippe Colletier
@es
Jacques-Philippe Colletier
@nl
Jacques-Philippe Colletier
@sl