The catalytic mechanism and structure of thymidylate synthase
about
Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviaePreliminary characterization of the protein encoded by human testis-enhanced gene transcript (TEGT)Bacteriophage T4 GenomeThe genome of Melanoplus sanguinipes entomopoxvirusBarriers to intron promiscuity in bacteria.RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shiftThe transcription factor LSF: a novel oncogene for hepatocellular carcinomaFlavin-Dependent Thymidylate Synthase as a New Antibiotic TargetCrystal structure of deoxycytidylate hydroxymethylase from bacteriophage T4, a component of the deoxyribonucleoside triphosphate-synthesizing complexCrystal structure of thymidylate synthase A from Bacillus subtilisSite-directed ligand discoveryStructure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitorsCrystal structure of a deletion mutant of human thymidylate synthase Δ (7-29) and its ternary complex with Tomudex and dUMPPhylogenetic classification of protozoa based on the structure of the linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate synthaseCooperative inhibition of human thymidylate synthase by mixtures of active site binding and allosteric inhibitors.Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformationThe R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195 † ‡Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: Calorimetric and crystallographic analysis of the K48Q mutantExplaining an Unusually Fast Parasitic Enzyme: Folate Tail-Binding Residues Dictate Substrate Positioning and Catalysis in Cryptosporidium hominis Thymidylate Synthase † ‡Structure of the cytosine-cytosine mismatch in the thymidylate synthase mRNA binding site and analysis of its interaction with the aminoglycoside paromomycinAn unusual mechanism of thymidylate biosynthesis in organisms containing the thyX geneReplacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability,Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand bindingProtein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthaseInhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovisFolate binding site of flavin-dependent thymidylate synthaseA Remote Mutation Affects the Hydride Transfer by Disrupting Concerted Protein Motions in Thymidylate SynthaseMechanistic and structural basis for inhibition of thymidylate synthase ThyXCrystallization ofChlorelladeoxyuridine triphosphataseCombining functional and structural genomics to sample the essential Burkholderia structomeMg 2+ Binds to the Surface of Thymidylate Synthase and Affects Hydride Transfer at the Interior Active SiteCrystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylaseFlavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor DesignThe structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolismCrystal Structure of Mouse Thymidylate Synthase in Tertiary Complex with dUMP and Raltitrexed Reveals N-Terminus Architecture and Two Different Active Site ConformationsDeprotonations in the Reaction of Flavin-Dependent Thymidylate SynthaseComprehensive structural and substrate specificity classification of the Saccharomyces cerevisiae methyltransferome.Oxidative Stress and Response to Thymidylate Synthase-Targeted AntimetabolitesKinetics and ligand-binding preferences of Mycobacterium tuberculosis thymidylate synthases, ThyA and ThyXTrypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase
P2860
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P2860
The catalytic mechanism and structure of thymidylate synthase
description
1995 nî lūn-bûn
@nan
1995 թուականին հրատարակուած գիտական յօդուած
@hyw
1995 թվականին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The catalytic mechanism and structure of thymidylate synthase
@ast
The catalytic mechanism and structure of thymidylate synthase
@en
The catalytic mechanism and structure of thymidylate synthase
@nl
type
label
The catalytic mechanism and structure of thymidylate synthase
@ast
The catalytic mechanism and structure of thymidylate synthase
@en
The catalytic mechanism and structure of thymidylate synthase
@nl
prefLabel
The catalytic mechanism and structure of thymidylate synthase
@ast
The catalytic mechanism and structure of thymidylate synthase
@en
The catalytic mechanism and structure of thymidylate synthase
@nl
P3181
P1476
The catalytic mechanism and structure of thymidylate synthase
@en
P2093
C W Carreras
P304
P3181
P356
10.1146/ANNUREV.BI.64.070195.003445
P407
P577
1995-01-01T00:00:00Z