Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
about
Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers.MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cellsStructural insight into the mechanism of synergistic autoinhibition of SAD kinasesMolecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase.MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies.CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials.Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase.
P2860
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P2860
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@ast
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@en
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@nl
type
label
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@ast
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@en
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@nl
prefLabel
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@ast
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@en
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@nl
P2093
P2860
P1433
P1476
Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase
@en
P2093
Haiteng Deng
Jia-Wei Wu
Lu-Sha Cao
Yuling Chen
Zhi-Xin Wang
P2860
P304
P356
10.1371/JOURNAL.PONE.0070031
P407
P577
2013-01-01T00:00:00Z