Optimization of an unnatural base pair toward natural-like replication
about
A semi-synthetic organism with an expanded genetic alphabetEfficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabetSolution Structure, Mechanism of Replication, and Optimization of an Unnatural Base PairKlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometryRecent advances in synthetic biosafetySynthetic constructs in/for the environment: managing the interplay between natural and engineered BiologyRB69 DNA polymerase structure, kinetics, and fidelity.DNA damage and interstrand cross-link formation upon irradiation of aryl iodide C-nucleotide analoguesMajor groove derivatization of an unnatural base pair.Synthetic biology: New letters for life's alphabet.A semisynthetic organism engineered for the stable expansion of the genetic alphabet.Structural basis for a six nucleotide genetic alphabet.Identification of DNA lesions using a third base pair for amplification and nanopore sequencing.The expanded genetic alphabet.Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair.Major groove substituents and polymerase recognition of a class of predominantly hydrophobic unnatural base pairs.The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation.Transcription of an expanded genetic alphabet.Synthesis at the interface of chemistry and biology.Non-natural nucleic acids for synthetic biology.Site-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs.Alternative DNA base-pairs: from efforts to expand the genetic code to potential material applications.Towards XNA nanotechnology: new materials from synthetic genetic polymersSynthetic chromosomes.In Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism.Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications.How do hydrophobic nucleobases differ from natural DNA nucleobases? Comparison of structural features and duplex properties from QM calculations and MD simulations.Synthetic Biology Parts for the Storage of Increased Genetic Information in Cells.Cycloadditions for Studying Nucleic Acids.Chemical Stabilization of Unnatural Nucleotide Triphosphates for the in Vivo Expansion of the Genetic Alphabet.PCR with an expanded genetic alphabet.Evolving a polymerase for hydrophobic base analogues.Selective transcription of an unnatural naphthyridine:imidazopyridopyrimidine base pair containing four hydrogen bonds with T7 RNA polymerase.Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology.A Tool for the Import of Natural and Unnatural Nucleoside Triphosphates into Bacteria.Reply to Hettinger: Hydrophobic unnatural base pairs and the expansion of the genetic alphabet.Structural Basis for Expansion of the Genetic Alphabet with an Artificial Nucleobase Pair.A cyclopropene-modified nucleotide for site-specific RNA labeling using genetic alphabet expansion transcription.
P2860
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P2860
Optimization of an unnatural base pair toward natural-like replication
description
2009 nî lūn-bûn
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2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
Optimization of an unnatural base pair toward natural-like replication
@ast
Optimization of an unnatural base pair toward natural-like replication
@en
type
label
Optimization of an unnatural base pair toward natural-like replication
@ast
Optimization of an unnatural base pair toward natural-like replication
@en
prefLabel
Optimization of an unnatural base pair toward natural-like replication
@ast
Optimization of an unnatural base pair toward natural-like replication
@en
P2093
P2860
P356
P1476
Optimization of an unnatural base pair toward natural-like replication
@en
P2093
Floyd E Romesberg
Phillip Ordoukhanian
Young Jun Seo
P2860
P304
P356
10.1021/JA807853M
P407
P577
2009-03-01T00:00:00Z