Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf
about
Recent syntheses of PI3K/Akt/mTOR signaling pathway inhibitors.Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization.Targeting PI3Kδ: emerging therapy for chronic lymphocytic leukemia and beyond.Molecular dynamics and integrated pharmacophore-based identification of dual [Formula: see text] inhibitors.From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome.Identification of new dual spleen tyrosine kinase (Syk) and phosphoionositide-3-kinase δ (PI3Kδ) inhibitors using ligand and structure-based integrated ideal pharmacophore models.
P2860
Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@ast
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@en
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@nl
type
label
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@ast
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@en
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@nl
prefLabel
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@ast
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@en
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@nl
P2093
P1476
Potent and selective inhibitor ...... ty pocket and tryptophan shelf
@en
P2093
Alan J Nadin
Angelina Bisconte
Anthony Brown
Binqing Wei
Bohdan Waszkowycz
Brian S Safina
Bryan K Chan
Cristina Lewis
Daniel P Sutherlin
David Chantry
P304
P356
10.1016/J.BMCL.2012.05.027
P407
P50
P577
2012-07-01T00:00:00Z