Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family.
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Review: Mechanochemistry of the kinesin-1 ATPaseKinesin-5 allosteric inhibitors uncouple the dynamics of nucleotide, microtubule, and neck-linker binding sites.Kinesin-2 KIF3AB exhibits novel ATPase characteristicsKinesin processivity is gated by phosphate releaseTEMPy: a Python library for assessment of three-dimensional electron microscopy density fitsKinesin-5 is a microtubule polymerase.Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins.High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generationCryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity.The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5.The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus.Visualizing microtubule structural transitions and interactions with associated proteins.Near-atomic cryo-EM structure of PRC1 bound to the microtubule.KIF15 promotes pancreatic cancer proliferation via the MEK-ERK signalling pathway.Eg5 Inhibitors Have Contrasting Effects on Microtubule Stability and Metaphase Spindle Integrity.Improved metrics for comparing structures of macromolecular assemblies determined by 3D electron-microscopy.Microtubule C-Terminal Tails Can Change Characteristics of Motor Force Production.The Kinesin-5 Chemomechanical Cycle Is Dominated by a Two-heads-bound State.The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.The yeast kinesin-5 Cin8 interacts with the microtubule in a noncanonical manner.Structural insight into TPX2-stimulated microtubule assembly.Structural basis of human kinesin-8 function and inhibition.Kinesin motility is driven by subdomain dynamics.A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function.
P2860
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P2860
Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family.
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2014 nî lūn-bûn
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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Comprehensive structural model ...... ptations in the kinesin family
@nl
Comprehensive structural model ...... tations in the kinesin family.
@ast
Comprehensive structural model ...... tations in the kinesin family.
@en
type
label
Comprehensive structural model ...... ptations in the kinesin family
@nl
Comprehensive structural model ...... tations in the kinesin family.
@ast
Comprehensive structural model ...... tations in the kinesin family.
@en
prefLabel
Comprehensive structural model ...... ptations in the kinesin family
@nl
Comprehensive structural model ...... tations in the kinesin family.
@ast
Comprehensive structural model ...... tations in the kinesin family.
@en
P2093
P2860
P3181
P356
P1476
Comprehensive structural model ...... ptations in the kinesin family
@en
P2093
Carolyn A Moores
Jennifer Major
Steven P Gross
Steven S Rosenfeld
Yonggun Jun
P2860
P304
P3181
P356
10.1073/PNAS.1319848111
P407
P577
2014-01-21T00:00:00Z