More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules
about
Cryo-EM of viruses and vaccine designMechanisms of virus assemblyHepatitis A virus and the origins of picornaviruses.Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis.Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to EnterovirusesPrioritization of active antimalarials using structural interaction profile of Plasmodium falciparum enoyl-acyl carrier protein reductase (PfENR)-triclosan derivatives.Cyclophilin A associates with enterovirus-71 virus capsid and plays an essential role in viral infection as an uncoating regulatorThe capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication.Peptidyl aldehyde NK-1.8k suppresses enterovirus 71 and enterovirus 68 infection by targeting protease 3CAnalysis of Enterovirus 68 Strains from the 2014 North American Outbreak Reveals a New Clade, Indicating Viral Evolution.Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.Studies on Inhibition of Proliferation of Enterovirus-71 by Compound YZ-LY-0.Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16.Hepatitis B Virus Capsids Have Diverse Structural Responses to Small-Molecule Ligands Bound to the Heteroaryldihydropyrimidine PocketAntiviral activity of micafungin against enterovirus 71.Amphotericin B Inhibits Enterovirus 71 Replication by Impeding Viral Entry.Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site.In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71.Hydrophobic pocket targeting probes for enteroviruses.A computational protocol to evaluate the effects of protein mutants in the kinase gatekeeper position on the binding of ATP substrate analogues.Equine Rhinitis A Virus Mutants with Altered Acid Resistance Unveil a Key Role of VP3 and Intrasubunit Interactions in the Control of the pH Stability of the Aphthovirus Capsid.Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD.Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine.Virus-inhibiting activity of dihydroquercetin, a flavonoid from Larix sibirica, against coxsackievirus B4 in a model of viral pancreatitis.Hepatitis A virus exhibits a structure unique among picornaviruses.Evaluation of a range of mammalian and mosquito cell lines for use in Chikungunya virus research.Etiology, pathogenesis, antivirals and vaccines of hand, foot, and mouth diseaseAntiviral Agents From Fungi: Diversity, Mechanisms and Potential ApplicationsSmall molecules targeting coxsackievirus A16 capsid inactivate viral particles and prevent viral binding
P2860
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P2860
More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@ast
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@en
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@nl
type
label
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@ast
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@en
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@nl
prefLabel
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@ast
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@en
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@nl
P2093
P2860
P50
P3181
P356
P1476
More-powerful virus inhibitors ...... HEV71 capsid-binding molecules
@en
P2093
James Kelly
John A B Spyrou
Jonathan Grimes
Junzhi Wang
Luigi De Colibus
Xiangxi Wang
Zhongyu Hu
P2860
P2888
P3181
P356
10.1038/NSMB.2769
P50
P577
2014-03-01T00:00:00Z
P5875
P6179
1015075701