Refined crystal structure of beta-lactamase from Citrobacter freundii indicates a mechanism for beta-lactam hydrolysis
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Plasmid-determined AmpC-type beta-lactamases.Three decades of beta-lactamase inhibitorsThe crystal structure of a penicilloyl-serine transferase of intermediate penicillin sensitivity. The DD-transpeptidase of streptomyces K15The complexed structure and antimicrobial activity of a non-β-lactam inhibitor of AmpC β-lactamaseEstB from Burkholderia gladioli: A novel esterase with a β-lactamase fold reveals steric factors to discriminate between esterolytic and β-lactam cleaving activityStructural basis for imipenem inhibition of class C beta-lactamases.Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complexHydrolysis of third-generation cephalosporins by class C beta-lactamases. Structures of a transition state analog of cefotoxamine in wild-type and extended spectrum enzymesRe-examining the role of Lys67 in class C β-lactamase catalysisStructure of AmpC β-lactamase (AmpCD) from anEscherichia coliclinical isolate with a tripeptide deletion (Gly286-Ser287-Asp288) in the H10 helixDirected Evolution and Structural Characterization of a Simvastatin SynthaseStructure of the extended-spectrum class C β-lactamase ADC-1 fromAcinetobacter baumanniiStructural analysis of the Asn152Gly mutant of P99 cephalosporinaseAvibactam and Class C -Lactamases: Mechanism of Inhibition, Conservation of the Binding Pocket, and Implications for ResistanceCrystal structure analysis of EstA from Arthrobacter sp. Rue61a--an insight into catalytic promiscuityFlexibility Correlation between Active Site Regions Is Conserved across Four AmpC β-Lactamase EnzymesBeta-lactamase TEM1 of E. coli. Crystal structure determination at 2.5 A resolutionKinetics and mechanism of inhibition of a serine beta-lactamase by O-aryloxycarbonyl hydroxamatesAmino acid sequence determinants of extended spectrum cephalosporin hydrolysis by the class C P99 beta-lactamase.pKa measurements from nuclear magnetic resonance of tyrosine-150 in class C beta-lactamase.Identification of residues critical for catalysis in a class C beta-lactamase by combinatorial scanning mutagenesis.The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution.A new family of cyanobacterial penicillin-binding proteins. A missing link in the evolution of class A beta-lactamases.Developing bifunctional beta-lactamase molecules with built-in target-recognizing module for prodrug therapy: identification of Enterobacter Cloacae P99 cephalosporinase loops suitable for randomization and phage-display selection.Enhancing resistance to cephalosporins in class C beta-lactamases: impact of Gly214Glu in CMY-2.Inhibition of the class C beta-lactamase from Acinetobacter spp.: insights into effective inhibitor design.Substituted aryl malonamates as new serine beta-lactamase substrates: structure-activity studiesFLAP pharmacological blockade modulates metabolism of endogenous tau in vivo .Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases.Carbapenem resistance in Escherichia coli associated with plasmid-determined CMY-4 beta-lactamase production and loss of an outer membrane protein.Reclaiming the efficacy of β-lactam-β-lactamase inhibitor combinations: avibactam restores the susceptibility of CMY-2-producing Escherichia coli to ceftazidime.Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.Evidence that the catalytic activity of prokaryote leader peptidase depends upon the operation of a serine-lysine catalytic dyadSerendipitous discovery of α-hydroxyalkyl esters as β-lactamase substrates.Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamase.Exploring sequence requirements for C₃/C₄ carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase.Primary structure of OXA-3 and phylogeny of oxacillin-hydrolyzing class D beta-lactamasesExtended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure.Stereoselective production of (+)-trans-chrysanthemic acid by a microbial esterase: cloning, nucleotide sequence, and overexpression of the esterase gene of Arthrobacter globiformis in Escherichia coli.Internal water molecules and H-bonding in biological macromolecules: a review of structural features with functional implications.
P2860
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P2860
Refined crystal structure of beta-lactamase from Citrobacter freundii indicates a mechanism for beta-lactam hydrolysis
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@ast
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@en
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@nl
type
label
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@ast
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@en
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@nl
prefLabel
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@ast
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@en
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@nl
P2093
P356
P1433
P1476
Refined crystal structure of b ...... ism for beta-lactam hydrolysis
@en
P2093
C Hubschwerlen
F K Winkler
K Gubernator
R L Charnas
P2888
P356
10.1038/343284A0
P407
P577
1990-01-18T00:00:00Z
P6179
1047724443