Evidence that the catalytic activity of prokaryote leader peptidase depends upon the operation of a serine-lysine catalytic dyad
about
SipA is required for pilus formation in Streptococcus pyogenes serotype M3The catalytic mechanism of endoplasmic reticulum signal peptidase appears to be distinct from most eubacterial signal peptidases.Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configurationA Target-Based Whole Cell Screen Approach To Identify Potential Inhibitors of Mycobacterium tuberculosis Signal PeptidaseMaturation of IncP pilin precursors resembles the catalytic Dyad-like mechanism of leader peptidases.Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library.Protein transport via amino-terminal targeting sequences: common themes in diverse systems.A novel transposon construct expressing PhoA with potential for studying protein expression and translocation in Mycoplasma gallisepticum.Characterization of a cDNA encoding the thylakoidal processing peptidase from Arabidopsis thaliana. Implications for the origin and catalytic mechanism of the enzyme.Molecular and functional analysis of the lepB gene, encoding a type I signal peptidase from Rickettsia rickettsii and Rickettsia typhi.Membrane proteases in the bacterial protein secretion and quality control pathway.The chemistry and enzymology of the type I signal peptidasesIdentification of the potential active site of the signal peptidase SipS of Bacillus subtilis. Structural and functional similarities with LexA-like proteases.Biochemical characterization of signal peptidase I from gram-positive Streptococcus pneumoniae.Regulated expression of the Escherichia coli lepB gene as a tool for cellular testing of antimicrobial compounds that inhibit signal peptidase I in vitroIdentification of a regulated alkaline phosphatase, a cell surface-associated lipoprotein, in Mycobacterium smegmatis.Molecular cloning and expression of the spsB gene encoding an essential type I signal peptidase from Staphylococcus aureusA specific protease encoded by the conjugative DNA transfer systems of IncP and Ti plasmids is essential for pilus synthesis.Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidasesCloning, expression, and purification of functional Sec11a and Sec11b, type I signal peptidases of the archaeon Haloferax volcanii.Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor.Inhibition of the sole type I signal peptidase of Mycobacterium tuberculosis is bactericidal under replicating and nonreplicating conditions.In vitro and in vivo self-cleavage of Streptococcus pneumoniae signal peptidase I.Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I.Identification of arginine residues important for the activity of Escherichia coli signal peptidase I.The identification of residues that control signal peptidase cleavage fidelity and substrate specificity.The Sec System: Protein Export in Escherichia coli.Phosphatidylethanolamine mediates insertion of the catalytic domain of leader peptidase in membranes.Prion protein structural features indicate possible relations to signal peptidases.The role of the conserved box E residues in the active site of the Escherichia coli type I signal peptidase.Use of site-directed chemical modification to study an essential lysine in Escherichia coli leader peptidase.
P2860
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P2860
Evidence that the catalytic activity of prokaryote leader peptidase depends upon the operation of a serine-lysine catalytic dyad
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@ast
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@en
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@nl
type
label
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@ast
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@en
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@nl
prefLabel
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@ast
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@en
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@nl
P2860
P1476
Evidence that the catalytic ac ...... a serine-lysine catalytic dyad
@en
P2093
P2860
P304
P356
10.1128/JB.175.16.4957-4961.1993
P407
P577
1993-08-01T00:00:00Z