A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation - Wikidata - awgldk - TriplyDB

A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation

A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation

http://www.wikidata.org/entity/Q27683382

about

Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systems Linking Α to Ω: diverse and dynamic RNA-based mechanisms to regulate gene expression by 5′-to-3′ communication Active Site Conformational Dynamics Are Coupled to Catalysis in the mRNA Decapping Enzyme Dcp2 In Vitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability A human microprotein that interacts with the mRNA decapping complex Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development.HAX-1: a novel p-body protein.Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.HPat a decapping activator interacting with the miRNA effector complex.A genome-wide tethering screen reveals novel potential post-transcriptional regulators in Trypanosoma brucei.Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper.General and MicroRNA-Mediated mRNA Degradation Occurs on Ribosome Complexes in Drosophila Cells.RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1.Standing your ground to exoribonucleases: Function of Flavivirus long non-coding RNAs.The 5'-3' exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277-3p in Drosophila wing imaginal discs.mRNA decapping enzyme 1a (Dcp1a)-induced translational arrest through protein kinase R (PKR) activation requires the N-terminal enabled vasodilator-stimulated protein homology 1 (EVH1) domain.Argonaute and GW182 proteins: an effective alliance in gene silencing.The role of disordered protein regions in the assembly of decapping complexes and RNP granules.Noncoding subgenomic flavivirus RNA: multiple functions in West Nile virus pathogenesis and modulation of host responses.The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1.Dicer-independent processing of short hairpin RNAs.The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface.Cellular 5'-3' mRNA exonuclease Xrn1 controls double-stranded RNA accumulation and anti-viral responses.miRISC recruits decapping factors to miRNA targets to enhance their degradation.Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast.Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences.Pervasive yet nonuniform contributions of Dcp2 and Cnot7 to maternal mRNA clearance in zebrafish.A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.An in vivo proteomic analysis of the Me31B interactome in Drosophila germ granules.Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.Dissecting the functions of SMG5, SMG7 and PNRC2 in nonsense-mediated mRNA decay of human cells.Phosphoproteomic analysis identifies proteins involved in transcription-coupled mRNA decay as targets of Snf1 signaling.Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

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P2860

A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation

http://www.wikidata.org/entity/Q27683382

description

2012 nî lūn-bûn

@nan

2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

A direct interaction between D ...... 5' exonucleolytic degradation

@ast

A direct interaction between D ...... 5' exonucleolytic degradation

@en

A direct interaction between D ...... 5' exonucleolytic degradation

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type

label

A direct interaction between D ...... 5' exonucleolytic degradation

@ast

A direct interaction between D ...... 5' exonucleolytic degradation

@en

A direct interaction between D ...... 5' exonucleolytic degradation

@nl

prefLabel

A direct interaction between D ...... 5' exonucleolytic degradation

@ast

A direct interaction between D ...... 5' exonucleolytic degradation

@en

A direct interaction between D ...... 5' exonucleolytic degradation

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P1433

Nature Structural & Molecular Biology

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A direct interaction between D ...... 5' exonucleolytic degradation

@en

P2093

Andreas Boland

http://www.w3.org/2001/XMLSchema#string

Chung-Te Chang

http://www.w3.org/2001/XMLSchema#string

Gabrielle Haas

http://www.w3.org/2001/XMLSchema#string

Murray Coles

http://www.w3.org/2001/XMLSchema#string

P2860

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs

Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping

Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity

A Sm-like protein complex that participates in mRNA degradation

MolProbity: all-atom structure validation for macromolecular crystallography

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Mechanisms of deadenylation-dependent decay

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P304

1324-31

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scholarly article

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3975441

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10.1038/NSMB.2413

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12

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19

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Elisa Izaurralde

Oliver Weichenrieder

Vincent Truffault

Eric Huntzinger

P577

2012-12-01T00:00:00Z

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1030004014

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P698

23142987

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