about
Structural basis for conductance through TRIC cation channels.Structure of IP3R channel: high-resolution insights from cryo-EM.Investigating the inter-subunit/subdomain interactions and motions relevant to disease mutations in the N-terminal domain of ryanodine receptors by molecular dynamics simulation.FK506-binding proteins 12 and 12.6 (FKBPs) as regulators of cardiac Ryanodine Receptors: Insights from new functional and structural knowledge.Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor.Mapping Ryanodine Binding Sites in the Pore Cavity of Ryanodine Receptors.Determination of the ribosome structure to a resolution of 2.5 Å by single-particle cryo-EM.The Cytoplasmic Region of Inner Helix S6 Is an Important Determinant of Cardiac Ryanodine Receptor Channel Gating.Ca2+ Release Channels Join the 'Resolution Revolution'.Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling.The N-Terminal Region of the Ryanodine Receptor Affects Channel Activation.IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography.STIM2 regulates both intracellular Ca2+ distribution and Ca2+ movement in skeletal myotubes.The structural basis of ryanodine receptor ion channel function.IP3 receptor signaling and endothelial barrier function.Intracellular calcium release channels: an update.Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy.New Opportunities Created by Single-Particle Cryo-EM: The Mapping of Conformational Space.Physiology and pathophysiology of excitation-contraction coupling: the functional role of ryanodine receptor.Control of cardiac ryanodine receptor by sarcoplasmic reticulum luminal Ca2.Perspectives on "Control of Ca release from within the cardiac sarcoplasmic reticulum".Reduced threshold for store overload-induced Ca2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease.G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to cytosolic and luminal Ca2.Ryanodine Receptor Structure and Function in Health and Disease.Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes.Ryanodine receptor resolution revolution: Implications for InsP3 receptors?Lanthanides Report Calcium Sensor in the Vestibule of Ryanodine Receptor.Novel Variants in Individuals with RYR1-Related Congenital Myopathies: Genetic, Laboratory, and Clinical Findings.Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5.Comparative analysis of FKBP family protein: evaluation, structure, and function in mammals and Drosophila melanogaster.Calcium-induced release of calcium in muscle: 50 years of work and the emerging consensus.In silico assessment of the conduction mechanism of the Ryanodine Receptor 1 reveals previously unknown exit pathways.Anticancer Activity of Euplotin C, Isolated from the Marine Ciliate Euplotes crassus, Against Human Melanoma Cells.A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca sensitivityPromiscuous attraction of ligands within the ATP binding site of RyR2 promotes diverse gating behaviourCorrelation of phenotype with genotype and protein structure in RYR1-related disorders
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Structural Basis for Gating and Activation of RyR1
@nl
Structural Basis for Gating and Activation of RyR1.
@ast
Structural Basis for Gating and Activation of RyR1.
@en
type
label
Structural Basis for Gating and Activation of RyR1
@nl
Structural Basis for Gating and Activation of RyR1.
@ast
Structural Basis for Gating and Activation of RyR1.
@en
prefLabel
Structural Basis for Gating and Activation of RyR1
@nl
Structural Basis for Gating and Activation of RyR1.
@ast
Structural Basis for Gating and Activation of RyR1.
@en
P2093
P2860
P1433
P1476
Structural Basis for Gating and Activation of RyR1.
@en
P2093
Andrew R Marks
Kendall J Condon
Oliver B Clarke
Robert A Grassucci
Wayne A Hendrickson
P2860
P304
145-157.e17
P356
10.1016/J.CELL.2016.08.075
P407
P577
2016-09-01T00:00:00Z