Structure of the regulatory domains of the Src-family tyrosine kinase Lck
about
The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cellsTyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of LckA novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signalingThe conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisalCharacterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinaseStructural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide.Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from SosCrystal structure of mammalian alpha1,6-fucosyltransferase, FUT8Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector moleculesA unique set of SH3-SH3 interactions controls IB1 homodimerization.Binding of Vav to Grb2 through dimerization of Src homology 3 domainsMutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactionsA single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef proteinStructure of the SH3 domain of human osteoclast-stimulating factor at atomic resolutionp95vav associates with the nuclear protein Ku-70Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopyThe role of the Src homology 3-Src homology 2 interface in the regulation of Src kinasesAn Src homology 3-like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation MechanismHigh-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptidesCrystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexesStructural basis for specificity of Grb2-SH2 revealed by a novel ligand binding modeC2 domain conformational changes in phospholipase C-delta 177 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic linkProline-rich sequences that bind to Src homology 3 domains with individual specificitiesInteraction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitmentPartial cooperative unfolding in proteins as observed by hydrogen exchange mass spectrometry.SH2-dependent autophosphorylation within the Tec family kinase Itk.Structure, stability, and flexibility of ribosomal protein L14e from Sulfolobus solfataricusOn the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases.Altered dynamics in Lck SH3 upon binding to the LBD1 domain of Herpesvirus saimiri TipCrystallization of the SH2-binding site of p130Cas in complex with Lck, a Src-family kinase.Structural basis for recognition of the T cell adaptor protein SLP-76 by the SH3 domain of phospholipase Cgamma1Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signalingThe lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.
P2860
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P2860
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@ast
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@en
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@nl
type
label
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@ast
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@en
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@nl
prefLabel
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@ast
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@en
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@nl
P2093
P3181
P356
P1433
P1476
Structure of the regulatory domains of the Src-family tyrosine kinase Lck
@en
P2093
S C Harrison
S E Shoelson
S K Atwell
P2888
P3181
P356
10.1038/368764A0
P407
P577
1994-04-21T00:00:00Z
P6179
1026759430