Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
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Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signalingA novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signalingFunctional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancerUbiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingThe Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and DiseaseDocking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory moleculesThe SH2 domain-containing proteins in 21 species establish the provenance and scope of phosphotyrosine signaling in eukaryotesRole of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes.On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.Identification of genes responsive to solar simulated UV radiation in human monocyte-derived dendritic cells.B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure.Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v.Sin: good or bad? A T lymphocyte perspective.Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain.Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling.SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice.Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modificationsNegative feedback of T cell activation through inhibitory adapters and costimulatory receptors.Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner.Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targetsSrc-like adaptor protein regulates osteoclast generation and survival.Mechanism of upregulation of the inhibitory regulator, src-like adaptor protein (SLAP), by glucocorticoids in mast cells.Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells and acts as a negative regulator.Differential involvement of E2A-corepressor interactions in distinct leukemogenic pathways.Transcriptomic Profiling of Virus-Host Cell Interactions following Chicken Anaemia Virus (CAV) Infection in an In Vivo Model.Protein kinase C theta cooperates with Vav1 to induce JNK activity in T-cells.Activation of EphA receptors mediates the recruitment of the adaptor protein Slap, contributing to the downregulation of N-methyl-D-aspartate receptors.Synergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 homolog MS4A8A.Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia.Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation.Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl.Negative regulation of immunoreceptor signaling by protein adapters: Shc proteins join the club.EMBO WORKSHOP REPORT: lymphocyte antigen receptor and coreceptor signaling Siena, Italy, November 6-10, 1999.Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.
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P2860
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
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2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
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Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
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Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
@ast
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
@en
prefLabel
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
@ast
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
@en
P2093
P2860
P356
P1476
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
@en
P2093
P2860
P304
P356
10.1084/JEM.191.3.463
P407
P577
2000-02-01T00:00:00Z