Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
about
SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate mannerThe role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signalingDifferential interactions of human Sos1 and Sos2 with Grb2Novel recognition mode between Vav and Grb2 SH3 domainsDiverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domainHigh-resolution crystal structure of spectrin SH3 domain fused with a proline-rich peptideGRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complexThe C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motifInteraction between the amino-terminal SH3 domain of CRK and its natural target proteinsQuantifying intramolecular binding in multivalent interactions: a structure-based synergistic study on Grb2-Sos1 complexFunctional analysis of the nucleotide binding domain of membrane-associated guanylate kinases.Organization and ligand binding properties of the tail of Acanthamoeba myosin-IA. Identification of an actin-binding site in the basic (tail homology-1) domain.SH3 domain of Bruton's tyrosine kinase can bind to proline-rich peptides of TH domain of the kinase and p120cbl.Predicted structure of the extracellular region of ligand-gated ion-channel receptors shows SH2-like and SH3-like domains forming the ligand-binding siteAdapter molecules in T cell receptor signaling.Assembly of the Sos1-Grb2-Gab1 ternary signaling complex is under allosteric controlSrc inhibitors: genomics to therapeutics.High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia.Prediction of the three-dimensional structure of proteins using the electrostatic screening model and hierarchic condensation.
P2860
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P2860
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@ast
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@en
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@nl
type
label
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@ast
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@en
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@nl
prefLabel
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@ast
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@en
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@nl
P2093
P1433
P1476
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2
@en
P2093
H Hatanaka
H Terasawa
J Schlessinger
S Ichikawa
V Mandiyan
P304
P356
10.1016/S0969-2126(94)00106-5
P577
1994-11-01T00:00:00Z