Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
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A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to RhoStructural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesiumA novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activationConditional activation defect of a human Gsalpha mutantMissense mutation in the gene encoding the alpha subunit of rod transducin in the Nougaret form of congenital stationary night blindnessFunctional expression of the taste specific G-protein, alpha-gustducinInteraction sites of the C-terminal region of the cGMP phosphodiesterase inhibitory subunit with the GDP-bound transducin alpha-subunitRas-catalyzed hydrolysis of GTP: a new perspective from model studiesThe structural basis of arrestin-mediated regulation of G-protein-coupled receptorsSwitches, latches, and amplifiers: common themes of G proteins and molecular motorsThe beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membraneComputational Simulation of the Activation Cycle of Gα Subunit in the G Protein Cycle Using an Elastic Network ModelComparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicasesAn open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanismStructural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognitionStructural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activityHelix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gα i Subunits † , ‡Structural basis for the specific inhibition of heterotrimeric Gq protein by a small moleculeA P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal PathogenesisA Constitutively Active Gα Subunit Provides Insights into the Mechanism of G Protein ActivationA switch III motif relays signaling between a B12 enzyme and its G-protein chaperoneA transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1.The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal formsCrystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilusCrystal structure of RhoA-GDP and its functional implicationsLight-activated rhodopsin induces structural binding motif in G protein alpha subunitCrystal structure of human RhoA in a dominantly active form complexed with a GTP analogueStructural determinants involved in the formation and activation of G protein betagamma dimers.The G beta gamma complex of the yeast pheromone response pathway. Subcellular fractionation and protein-protein interactions.RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor ActivityExpression, purification, and characterization of a novel G protein, SGP, from Streptococcus mutansCell-Autonomous Gβ Signaling Defines Neuron-Specific Steady State Serotonin Synthesis in Caenorhabditis elegansIntersubunit Surfaces in G Protein alphabeta[IMAGE] HeterotrimersG protein signaling: insights from new structures.Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins.Activated alleles of the Schizosaccharomyces pombe gpa2+ Galpha gene identify residues involved in GDP-GTP exchange.Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution.Involvement of N-myristoylation in monoclonal antibody recognition sites on chimeric G protein alpha subunits.A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteinsMapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.
P2860
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P2860
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@ast
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@en
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@nl
type
label
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@ast
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@en
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@nl
prefLabel
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@ast
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@en
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@nl
P2093
P3181
P356
P1433
P1476
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein
@en
P2093
D G Lambright
P B Sigler
P2888
P3181
P356
10.1038/369621A0
P407
P577
1994-06-23T00:00:00Z
P6179
1037031151