The nuclear magnetic resonance solution structure of flavoridin, an antagonist of the platelet GP IIb-IIIa receptor
about
Conformation and concerted dynamics of the integrin-binding site and the C-terminal region of echistatin revealed by homonuclear NMRStructure of acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix), at 1.7 Å resolutionNMR structure and dynamics of recombinant wild type and mutated jerdostatin, a selective inhibitor of integrin α1β1Structure of Protein Having Inhibitory Disintegrin and Leukotriene Scavenging Functions Contained in Single DomainNMR structure of bitistatin – a missing piece in the evolutionary pathway of snake venom disintegrinsThree-dimensional structure of the RGD-containing neurotoxin homologue dendroaspinEvaluation of the role of proline residues flanking the RGD motif of dendroaspin, an inhibitior of platelet aggregation and cell adhesionInsights into and speculations about snake venom metalloproteinase (SVMP) synthesis, folding and disulfide bond formation and their contribution to venom complexity.Savignygrin, a platelet aggregation inhibitor from the soft tick Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold.Disulphide-bond pattern and molecular modelling of the dimeric disintegrin EMF-10, a potent and selective integrin alpha5beta1 antagonist from Eristocophis macmahoni venom.Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition.Enhanced conformational sampling in Monte Carlo simulations of proteins: application to a constrained peptide.Effect of P to A mutation of the N-terminal residue adjacent to the Rgd motif on rhodostomin: importance of dynamics in integrin recognition.The disulphide bond pattern of bitistatin, a disintegrin isolated from the venom of the viper Bitis arietans.ADAM-15 disintegrin-like domain structure and function.Recombinant decorsin: dynamics of the RGD recognition site.A peptide inhibiting the collagen binding function of integrin alpha2I domain.Contortrostatin, a homodimeric disintegrin, actively disrupts focal adhesion and cytoskeletal structure and inhibits cell motility through a novel mechanism.Amino acid sequence and homology modeling of obtustatin, a novel non-RGD-containing short disintegrin isolated from the venom of Vipera lebetina obtusa.The integrin alpha IIb beta 3 contains distinct and interacting binding sites for snake-venom RGD (Arg-Gly-Asp) proteins. Evidence that the receptor-binding characteristics of snake-venom RGD proteins are related to the amino acid environment flankiA conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin.Determination of the structure of two novel echistatin variants and comparison of the ability of echistatin variants to inhibit aggregation of platelets from different species.Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering.Integrin receptors play a role in the internalin B-dependent entry of Listeria monocytogenes into host cells.Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.Characterization of a monomeric disintegrin, ocellatusin, present in the venom of the Nigerian carpet viper, Echis ocellatus.Substitutions of proline 42 to alanine and methionine 46 to asparagine around the RGD domain of the neurotoxin dendroaspin alter its preferential antagonism to that resembling the disintegrin elegantin.Expression inPichia pastoris and characterization by circular dichroism and NMR of rhodostominStructural Requirements of Echistatin for the Recognition of αvβ3and α5β1IntegrinsImportance of the structure of the RGD-containing loop in the disintegrins echistatin and eristostatin for recognition of αIIbβ3 and αvβ3 integrins
P2860
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P2860
The nuclear magnetic resonance solution structure of flavoridin, an antagonist of the platelet GP IIb-IIIa receptor
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@ast
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@en
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@nl
type
label
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@ast
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@en
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@nl
prefLabel
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@ast
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@en
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@nl
P356
P1476
The nuclear magnetic resonance ...... platelet GP IIb-IIIa receptor
@en
P304
P356
10.1006/JMBI.1993.1439
P407
P577
1993-08-05T00:00:00Z