Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering.
about
Antitumoral potential of Tunisian snake venoms secreted phospholipases A2Conformation and concerted dynamics of the integrin-binding site and the C-terminal region of echistatin revealed by homonuclear NMRDisintegrins from snake venoms and their applications in cancer research and therapy.Applications of snake venom components to modulate integrin activities in cell-matrix interactionsNMR structure of bitistatin – a missing piece in the evolutionary pathway of snake venom disintegrinsMetalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction SitesLebestatin, a disintegrin from Macrovipera venom, inhibits integrin-mediated cell adhesion, migration and angiogenesisA review on the Scorpaena plumieri fish venom and its bioactive compoundsMolecular cloning of disintegrins from Cerastes vipera and Macrovipera lebetina transmediterranea venom gland cDNA libraries: insight into the evolution of the snake venom integrin-inhibition system.Bioinformatics and multiepitope DNA immunization to design rational snake antivenomThe venom gland transcriptome of the Desert Massasauga rattlesnake (Sistrurus catenatus edwardsii): towards an understanding of venom composition among advanced snakes (Superfamily Colubroidea).Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition.The mojastin mutant Moj-DM induces apoptosis of the human melanoma SK-Mel-28, but not the mutant Moj-NN nor the non-mutated recombinant Moj-WN.Cloning, expression, and hemostatic activities of a disintegrin, r-mojastin 1, from the mohave rattlesnake (Crotalus scutulatus scutulatus).Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.ADAM-17: the enzyme that does it all.An insight into the sialotranscriptome of Simulium nigrimanum, a black fly associated with fogo selvagem in South America.Multimeric disintegrin protein polymer fusions that target tumor vasculature.Integrin alpha(v)beta(3)-Targeted Cancer Therapy.Recombinant rubistatin (r-Rub), an MVD disintegrin, inhibits cell migration and proliferation, and is a strong apoptotic inducer of the human melanoma cell line SK-Mel-28.cDNA cloning of a snake venom metalloproteinase from the eastern diamondback rattlesnake (Crotalus adamanteus), and the expression of its disintegrin domain with anti-platelet effects.Sexual differences in the sialomes of the zebra tick, Rhipicephalus pulchellus.Diversity of metalloproteinases in Bothrops neuwiedi snake venom transcripts: evidences for recombination between different classes of SVMPsAnti-metastatic activity of the recombinant disintegrin, r-mojastin 1, from the Mohave rattlesnakeNormal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics.Differences in binding of (99m)Tc-disintegrins to integrin alphavbeta3 on tumor and vascular cells.Centipede venoms as a source of drug leads.Snake venom disintegrins and cell migration.Domain loss facilitates accelerated evolution and neofunctionalization of duplicate snake venom metalloproteinase toxin genes.The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals.Cooperation of the metalloprotease, disintegrin, and cysteine-rich domains of ADAM12 during inhibition of myogenic differentiation.cDNA cloning, expression and fibrin(ogen)olytic activity of two low-molecular weight snake venom metalloproteinasesFibronectin-mediated upregulation of α5β1 integrin and cell adhesion during differentiation of mouse embryonic stem cells.cDNA cloning and functional expression of jerdostatin, a novel RTS-disintegrin from Trimeresurus jerdonii and a specific antagonist of the alpha1beta1 integrin.Structural and dynamical properties of KTS-disintegrins: A comparison between Obtustatin and Lebestatin.Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.Structural determinants of the selectivity of KTS-disintegrins for the alpha1beta1 integrin.CysMap and CysJoin: database and tools for protein disulphides localisation.Chemistry and Enzymology of Disulfide Cross-Linking in Proteins.Isolation and characterization of an anti-leishmanial disintegrin from Cerastes cerastes venom.
P2860
Q21285078-F7F097AA-44BC-43F0-B432-641134C6CCBEQ24528172-686FD1CD-E14C-4662-A6F6-FDC4861BDAD6Q27000037-5845513B-F3E0-4F79-9CFA-A17E15ADB93EQ27011302-A551611B-4087-4B39-A8D0-821542DD699CQ27696093-302CAB65-B31F-42F7-97E4-BEE623B80B2CQ28075348-1747EDAA-360A-415C-BD7F-B0961111DBD8Q28578254-2129090C-98F6-4E1B-8F66-DB08CE877ABFQ28818821-B0B1F3AE-6B5C-434E-8902-84ECF4267D16Q33231586-BCDA1B36-FA45-4690-B1FE-31D510109502Q33245264-F5DCFD66-1302-44F5-BA34-41D85E0E2A1FQ33311585-2016BFB4-9400-431F-BBD8-C6F878F8255FQ33554510-E4AE6262-282C-4B97-A726-64108627DD6DQ33558005-D25939C5-AA9F-4954-9A0F-C497B70F75BEQ33624340-47107ECE-1BCE-47DC-9D3B-4B7EDAA2F369Q33700519-E7897A69-7271-4E39-9A2D-5B944CA4C4BEQ33737421-35A7BCC7-7A95-47E7-B10F-D7438F0155F3Q33880640-9D0EB475-AD1E-4773-BC60-1B65D214736FQ33901479-6328A20B-B71D-431A-BC6D-1DFB55A21349Q33983773-6C2CEAE0-B102-4A09-86A7-29B68EA80616Q34109116-B4D947C5-C303-44DF-8A58-B71B23257954Q34546426-2CA31C70-4A00-4EE9-BC4F-A7EB0AE5D20FQ35220095-FFB40FA0-4DB6-4BC9-BA91-C03959A48982Q35554915-5D6D8A61-D9F1-49B9-B343-9A13FE210E83Q35801679-D7CA31CC-F3C8-42E3-A85F-2A258B3B1681Q35886876-96A2400E-4713-4A05-827D-620BF1EB9CF4Q36002728-05BB89CB-BCE5-4800-B866-A7749C59807CQ36128041-F642B6C5-0E51-4EB1-A4EE-834EAF7181DFQ37954274-EF644C2E-1E70-4A67-B835-38D6CC198660Q38933859-1B75AFF0-07FE-4D3F-B5E4-FFE37AA5D731Q39181842-1B5E1145-2877-4BDC-B16E-C2105B5DAC4AQ41853203-30B03934-7DA6-4CF1-96C8-A6860FD62AB0Q42324327-0983D127-F85B-44EB-A050-D6D83689AECEQ42598348-7BFD906C-897A-4C6D-BCEB-A76DFB158890Q42670285-9F14B946-53BD-42F7-B829-B65785830695Q43882311-A689CAE1-CCF4-41B7-8766-E9E581ACE97CQ44567823-4F7837D3-F04A-451C-95FF-65FA7E73571CQ45158279-DC23590B-B197-43EA-A4D2-AD8FDF7F667CQ46493030-51A1BF2C-39C1-4EF6-8B00-1ECCC066977AQ48139731-13209BDE-CB61-4E87-B8A1-443B821D0E38Q48349019-EC3BA9C3-EBA8-4E43-8C80-6C144653BB79
P2860
Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Snake venom disintegrins: nove ...... y disulphide bond engineering.
@en
Snake venom disintegrins: nove ...... y disulphide bond engineering.
@nl
type
label
Snake venom disintegrins: nove ...... y disulphide bond engineering.
@en
Snake venom disintegrins: nove ...... y disulphide bond engineering.
@nl
prefLabel
Snake venom disintegrins: nove ...... y disulphide bond engineering.
@en
Snake venom disintegrins: nove ...... y disulphide bond engineering.
@nl
P2093
P2860
P356
P1433
P1476
Snake venom disintegrins: nove ...... y disulphide bond engineering.
@en
P2093
Cezary Marcinkiewicz
Dariusz G Kisiel
M Paz Moreno-Murciano
P2860
P304
P356
10.1042/BJ20021739
P407
P577
2003-06-01T00:00:00Z