NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin
about
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugsFunctional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB proteinStructural basis of UV DNA-damage recognition by the DDB1-DDB2 complexDifferential activation of DNA-PK based on DNA strand orientation and sequence biasNoble metals in oncologyCrystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated siteHMG-D complexed to a bulge DNA: An NMR model2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplexSolution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link † , ‡Consequences of Cisplatin Binding on Nucleosome Structure and DynamicsFlanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-LinksStructural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapyTransition Metal Intercalators as Anticancer Agents-Recent AdvancesAnalysis of structural flexibility of damaged DNA using thiol-tethered oligonucleotide duplexesCharacterization of DNA recognition by the human UV-damaged DNA-binding proteinDNA oligonucleotide duplexes containing intramolecular platinated cross-links: energetics, hydration, sequence, and ionic effects.Cisplatin adducts of d(CCTCTG*G*TCTCC).d(GGAGACCAGAGG) in aqueous solution by vibrational circular dichroism spectroscopy.Molecular mechanisms and kinetics between DNA and DNA binding ligands.Preliminary study of mechanism of action of SN38 derivatives. Physicochemical data, evidence of interaction and alkylation of DNA octamer d(GCGATCGC)2.Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.Binding of kinetically inert metal ions to RNA: the case of platinum(II).DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesUnusual DNA binding modes for metal anticancer complexes.Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis.Thermodynamic and hydration effects for the incorporation of a cationic 3-aminopropyl chain into DNADDB1-DDB2 (xeroderma pigmentosum group E) protein complex recognizes a cyclobutane pyrimidine dimer, mismatches, apurinic/apyrimidinic sites, and compound lesions in DNA.Excursions in polynuclear platinum DNA binding.Oxaliplatin: a review of evolving concepts.Oxaliplatin: pre-clinical perspectives on the mechanisms of action, response and resistance.Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins.Modeling anticancer drug-DNA interactions via mixed QM/MM molecular dynamics simulations.Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase.Multiscale modeling of double-helical DNA and RNA: a unification through Lie groups.Cisplatin induces loop structures and condensation of single DNA molecules.Differential DNA lesion formation and repair in heterochromatin and euchromatinInhibition of transcription by platinum antitumor compoundsDifferential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin.Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics.Nucleolar control of p53: a cellular Achilles' heel and a target for cancer therapy.Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex.
P2860
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P2860
NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
NMR solution structure of a DN ...... the anticancer drug cisplatin
@ast
NMR solution structure of a DN ...... the anticancer drug cisplatin
@en
NMR solution structure of a DN ...... the anticancer drug cisplatin
@nl
type
label
NMR solution structure of a DN ...... the anticancer drug cisplatin
@ast
NMR solution structure of a DN ...... the anticancer drug cisplatin
@en
NMR solution structure of a DN ...... the anticancer drug cisplatin
@nl
prefLabel
NMR solution structure of a DN ...... the anticancer drug cisplatin
@ast
NMR solution structure of a DN ...... the anticancer drug cisplatin
@en
NMR solution structure of a DN ...... the anticancer drug cisplatin
@nl
P356
P1433
P1476
NMR solution structure of a DN ...... the anticancer drug cisplatin
@en
P2093
S J Lippard
P304
P356
10.1021/BI973176V
P407
P577
1998-06-30T00:00:00Z