Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.
about
Glutamate receptor poresModulation by permeant ions of Mg(2+) inhibition of NMDA-activated whole-cell currents in rat cortical neuronsHigh-affinity Zn block in recombinant N-methyl-D-aspartate receptors with cysteine substitutions at the Q/R/N site.Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytesNetwork-Based Approach to Identify Potential Targets and Drugs that Promote Neuroprotection and Neurorepair in Acute Ischemic StrokeGenetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces.Data-driven modeling of synaptic transmission and integration.Pharmacodynamics of memantine: an update.An N-methyl-D-aspartate receptor channel blocker with neuroprotective activity.AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins.GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine.Optocontrol of glutamate receptor activity by single side-chain photoisomerization.Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca2+ permeability and Mg2+ block.Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations.Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels.NMDA receptors mediate olfactory learning and memory in Drosophila.Targeting N-methyl-D-aspartate receptors for treatment of neuropathic painVoltage-dependent inhibition of recombinant NMDA receptor-mediated currents by 5-hydroxytryptamine.Mutations within the selectivity filter of the NMDA receptor-channel influence voltage dependent block by 5-hydroxytryptamine.All atom NMDA receptor transmembrane domain model development and simulations in lipid bilayers and water.Permeant ion regulation of N-methyl-D-aspartate receptor channel block by Mg(2+).Tonic and stimulus-evoked nitric oxide production in the mouse olfactory bulb.Open-channel blockade is less effective on GluN3B than GluN3A subunit-containing NMDA receptors.Chimeric Glutamate Receptor Subunits Reveal the Transmembrane Domain Is Sufficient for NMDA Receptor Pore Properties but Some Positive Allosteric Modulators Require Additional Domains.GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation.Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy.Influence of GluN2 subunit identity on NMDA receptor function.Interaction of metal ions with neurotransmitter receptors and potential role in neurodiseases.MODULATION OF N-METHYL-D-ASPARTATE RECEPTORS IN ISOLATED RAT HEART.Binding of ArgTX-636 in the NMDA receptor ion channelEffects of divalent cations on slow unblock of native NMDA receptors in mouse neocortical pyramidal neurons.Memantine binding to a superficial site on NMDA receptors contributes to partial trapping.Intersegment hydrogen bonds as possible structural determinants of the N/Q/R site in glutamate receptors.Modeling of the pore domain of the GLUR1 channel: homology with K+ channel and binding of channel blockers.NR2 subunit-dependence of NMDA receptor channel block by external Mg2+.Metal toxicity at the synapse: presynaptic, postsynaptic, and long-term effects.Amino acid substitutions in the pore of rat glutamate receptors at sites influencing block by polyamines.Intracellular Mg2+ interacts with structural determinants of the narrow constriction contributed by the NR1-subunit in the NMDA receptor channel.Na(+) occupancy and Mg(2+) block of the n-methyl-d-aspartate receptor channel.K(+) occupancy of the N-methyl-d-aspartate receptor channel probed by Mg(2+) block.
P2860
Q27021745-136410F1-26C3-4174-9849-00035386F0C6Q28344399-74C4E871-6D63-44B6-A94D-75666930C7CAQ28367644-81390D2F-D2EC-4ED1-AEA9-62C568D5205DQ28564813-7D28ECF4-924E-45AD-9F50-1914C26FD66EQ28584257-5E6166EF-48EA-42C5-AF57-5E446D4BB22AQ30361205-F0363D16-5D2B-4EA9-96E5-3BFF486B4D3CQ30391386-7E4ECC1E-D991-48F1-B461-1B1A5B69A6A6Q30490604-47DC4F43-5044-4B5E-8F73-D19ED3BA29B8Q30983394-0539DAC2-7945-4521-9719-559102A57E6BQ33204326-9D3F1BC7-3674-4656-8E05-EF5E5D514853Q33604210-EB9EEE73-6C60-4953-B0A7-489B49B887BCQ33719620-FFD5D0B6-3E60-4A04-A407-DE774CDC615AQ33722699-9FD02977-467D-4D58-B870-35F0D9411404Q34170194-F48BBFAB-8B4B-44AF-BFC2-8BE7993A4773Q34170543-EEC1E22D-23E4-4855-96E9-7BECC036E409Q34609071-FEBFF128-6DB2-461B-94EB-F7394539F2B8Q35041376-6559F96A-D128-4742-B18A-0233B5C223FDQ35048570-118BE148-ACFA-400C-A3CD-819E8F9157E9Q36052454-57F8EB26-5FF7-4144-8B4B-D0390BA52222Q36392889-644289F1-F3A4-4BCB-968C-6B9A79CBD188Q36749244-1AD99791-9B90-4B6F-93EE-82A93BB3DD54Q36777631-7899F250-DD41-4501-8438-4D52EEA646C5Q36852769-A4F2C7FC-A32B-4BEE-9233-38AE271AD033Q37198388-29723391-CCAC-4890-896F-C701274FA133Q37198498-6F3DBDAE-A153-404A-A185-53603AE3879BQ37603368-20D9AB0D-9DB8-4607-B560-C2803877668CQ38078685-90A0C9F0-5F24-4CB9-9750-390A2E0C3A50Q38249959-05D7549A-196C-4647-B2E8-CC924B1A2BEBQ38652337-5D5FF2A9-DD08-4099-A94D-7A3D601A016DQ39186423-0105A8C5-9478-4963-922D-AF5B2EE0C4CBQ39263189-F98D03E9-AA79-4A25-AA57-A05C560817B9Q39811514-714640D4-0F6E-4BF6-896F-DF1DE7803B53Q40150776-6D81990B-87EF-41CF-8FF7-141ACA28EBF9Q40204287-96E3EF39-63D5-4D60-8532-FFF18BB80B5BQ40498654-025C2A1F-716B-48D4-B2D9-5E5B7F808A47Q40582666-C364B19D-875D-4C83-B9E1-8B09A55A23EDQ40922838-34299409-2B06-4AD5-8F13-4E70BAF6D7B8Q41063217-BF9CB7C9-93F0-46A5-88CC-E929C523DF0DQ41814896-8314ECD3-E890-492A-ABD2-95FE4A9BE8E9Q41918145-A119D1E9-7991-4195-AB3D-DD1865C49701
P2860
Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@ast
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@en
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@nl
type
label
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@ast
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@en
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@nl
altLabel
Adjacent asparagines in the NR ...... nt block by extracellular Mg2+
@en
prefLabel
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@ast
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@en
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@nl
P2093
P2860
P1476
Adjacent asparagines in the NR ...... t block by extracellular Mg2+.
@en
P2093
P2860
P356
10.1111/J.1469-7793.1998.013BX.X
P407
P478
506 ( Pt 1)
P577
1998-01-01T00:00:00Z