An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions.
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Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.Ionic blockade of the rat connexin40 gap junction channel by large tetraalkylammonium ionsModulation of the inwardly rectifying potassium channel Kir4.1 by the pro-invasive miR-5096 in glioblastoma cellsPotassium current inhibition by nonselective cation channel-mediated sodium entry in rat pheochromocytoma (PC-12) cells.Channel blocking properties of a series of nicotinic cholinergic agonists.Blockade of HERG channels expressed in Xenopus laevis oocytes by external divalent cations.Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels.Block of the ryanodine receptor channel by neomycin is relieved at high holding potentialsVoltage-dependent blockade of connexin40 gap junctions by spermine.Revisiting voltage-dependent relief of block in ion channels: a mechanism independent of punchthrough.Comparison of the effects of internal TEA+ and Cs+ on potassium current in squid giant axons.Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations.Mechanisms of Cs+ blockade in a Ca2+-activated K+ channel from smooth muscle.Lack of effect of internal fluoride ions on potassium channels in squid axons.Hyaluronan export through plasma membranes depends on concurrent K+ efflux by K(ir) channels.Origins of ion selectivity in potassium channels from the perspective of channel block.Inhibition by quinine of endothelium-dependent relaxation of rabbit aortic strips.Interactions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins.Permeant ion effects on the gating kinetics of the type L potassium channel in mouse lymphocytesIon permeation, divalent ion block, and chemical modification of single sodium channels. Description by single- and double-occupancy rate-theory models.Methadone block of K+ current in squid giant fiber lobe neuronsThe interaction of Na+ and K+ in voltage-gated potassium channels. Evidence for cation binding sites of different affinity.Permeation, selectivity, and blockade of the Ca2+-activated potassium channel of the guinea pig taenia coli myocyte.Na+ block and permeation in a K+ channel of known structureRyanoid modification of the cardiac muscle ryanodine receptor channel results in relocation of the tetraethylammonium binding site.Permeation of large tetra-alkylammonium cations through mutant and wild-type voltage-gated sodium channels as revealed by relief of block at high voltageLack of negative slope in I-V plots for BK channels at positive potentials in the absence of intracellular blockers.Trans-channel interactions in batrachotoxin-modified rat skeletal muscle sodium channels: kinetic analysis of mutual inhibition between mu-conotoxin GIIIA derivatives and amine blockersTrans-channel interactions in batrachotoxin-modified skeletal muscle sodium channels: voltage-dependent block by cytoplasmic amines, and the influence of mu-conotoxin GIIIA derivatives and permeant ionsProperties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums.Amphiphilic blockers punch through a mutant CLC-0 pore.Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study.Blocking mechanisms of batrachotoxin-activated Na channels in artificial bilayers.Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.Modulation of C-type inactivation by K+ at the potassium channel selectivity filter.TRPV1 regulators mediate gentamicin penetration of cultured kidney cells.Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.Regulation of transient Na+ conductance by intra- and extracellular K+ in the human delayed rectifier K+ channel Kv1.5.The relation between ion permeation and recovery from inactivation of ShakerB K+ channels.Open-state stabilization in Kv channels: voltage-sensor relaxation and pore propping by a bound ion.
P2860
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P2860
An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
An ion's view of the potassium ...... by a variety of blocking ions.
@ast
An ion's view of the potassium ...... by a variety of blocking ions.
@en
type
label
An ion's view of the potassium ...... by a variety of blocking ions.
@ast
An ion's view of the potassium ...... by a variety of blocking ions.
@en
prefLabel
An ion's view of the potassium ...... by a variety of blocking ions.
@ast
An ion's view of the potassium ...... by a variety of blocking ions.
@en
P2860
P356
P1476
An ion's view of the potassium ...... by a variety of blocking ions.
@en
P2093
J J Shoukimas
R J French
P2860
P304
P356
10.1085/JGP.85.5.669
P577
1985-05-01T00:00:00Z