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Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2betaCrystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointMad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochoresMammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphaseStructure-Based Design of Orally Bioavailable 1 H -Pyrrolo[3,2- c ]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p.CHL1 is a nuclear protein with an essential ATP binding site that exhibits a size-dependent effect on chromosome segregation.The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins.Defects in Saccharomyces cerevisiae protein phosphatase type I activate the spindle/kinetochore checkpoint.Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae.MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p.The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpointThe mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradationA human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2Transforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatusCell cycle in the fucus zygote parallels a somatic cell cycle but displays a unique translational regulation of cyclin-dependent kinasesKinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells.The maize homologue of the cell cycle checkpoint protein MAD2 reveals kinetochore substructure and contrasting mitotic and meiotic localization patterns.Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans.Cell cycle control, checkpoint mechanisms, and genotoxic stress.The metaphase to anaphase transition: a case of productive destruction.Dephosphorylation of cell cycle-regulated proteins correlates with anoxia-induced suspended animation in Caenorhabditis elegansComponents of the spindle-assembly checkpoint are essential in Caenorhabditis elegans.A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast.Defects in components of the proteasome enhance transcriptional silencing at fission yeast centromeres and impair chromosome segregation.Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.The pathology of familial breast cancer: How do the functions of BRCA1 and BRCA2 relate to breast tumour pathology?Effects of seawater acidification on cell cycle control mechanisms in Strongylocentrotus purpuratus embryos.The interaction between Ran and NTF2 is required for cell cycle progression.An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component.Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle functionVisualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells.Cdc28 activates exit from mitosis in budding yeast.Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis.Zfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes.Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent mannerThe fission yeast chromo domain encoding gene chp1(+) is required for chromosome segregation and shows a genetic interaction with alpha-tubulin.Genetic instability and the mutator phenotype. Studies in ulcerative colitis
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The spindle checkpoint.
@ast
The spindle checkpoint.
@en
The spindle checkpoint.
@nl
type
label
The spindle checkpoint.
@ast
The spindle checkpoint.
@en
The spindle checkpoint.
@nl
prefLabel
The spindle checkpoint.
@ast
The spindle checkpoint.
@en
The spindle checkpoint.
@nl
P3181
P1433
P1476
The spindle checkpoint.
@en
P2093
K G Hardwick
P3181
P356
10.1016/S0168-9525(97)01340-1
P407
P577
1998-01-01T00:00:00Z