Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells.
about
An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cellsUnstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F.The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosisDimerization of the CENP-A assembly factor HJURP is required for centromeric nucleosome depositionThe DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointZwilch, a new component of the ZW10/ROD complex required for kinetochore functionsClathrin is required for the function of the mitotic spindleSilencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.The SUMO protease SENP6 is essential for inner kinetochore assemblyIdentification of two novel components of the human NDC80 kinetochore complexTripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachmentsArchitecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochoreCyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosisThe human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome lossSpatiotemporal control of mitosis by the conserved spindle matrix protein MegatorIdentification of a MAD2-binding protein, CMT2, and its role in mitosis.Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transportCentrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylationMad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assemblyHuman Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindleCheckpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complexMicrotubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochoresHec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpointCytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivationA new view of the spindle checkpointCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cellshNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cellsHuman MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresStructural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template modelCyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphaseMG-132, an inhibitor of proteasomes and calpains, induced inhibition of oocyte maturation and aneuploidy in mouse oocytesFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisThe Renaissance or the cuckoo clockIntracellular spatial localization regulated by the microtubule network
P2860
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P2860
Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Visualization of Mad2 dynamics ...... spindle poles in living cells.
@ast
Visualization of Mad2 dynamics ...... spindle poles in living cells.
@en
type
label
Visualization of Mad2 dynamics ...... spindle poles in living cells.
@ast
Visualization of Mad2 dynamics ...... spindle poles in living cells.
@en
prefLabel
Visualization of Mad2 dynamics ...... spindle poles in living cells.
@ast
Visualization of Mad2 dynamics ...... spindle poles in living cells.
@en
P2093
P2860
P356
P1476
Visualization of Mad2 dynamics ...... spindle poles in living cells.
@en
P2093
P2860
P304
P356
10.1083/JCB.150.6.1233
P407
P577
2000-09-01T00:00:00Z