Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1)
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Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insightsThe Ubp15 deubiquitinase promotes timely entry into S phase in Saccharomyces cerevisiaeAcm1 is a negative regulator of the CDH1-dependent anaphase-promoting complex/cyclosome in budding yeast.Pseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation.Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle.Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifsCdc14 Early Anaphase Release, FEAR, Is Limited to the Nucleus and Dispensable for Efficient Mitotic Exit.The role of karyopherins in the regulated sumoylation of septins.Inhibition of APCCdh1 activity by Cdh1/Acm1/Bmh1 ternary complex formation.Ama1p-activated anaphase-promoting complex regulates the destruction of Cdc20p during meiosis II.Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteinsModulation of the mitotic regulatory network by APC-dependent destruction of the Cdh1 inhibitor Acm1.APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayNuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylationCdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicityThe anaphase promoting complex/cyclosome: a machine designed to destroyInsights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons.APC/C-CCS52A complexes control meristem maintenance in the Arabidopsis rootNuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle.E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferationRequirements and reasons for effective inhibition of the anaphase promoting complex activator CDH1.The karyopherin Kap95 and the C-termini of Rfa1, Rfa2, and Rfa3 are necessary for efficient nuclear import of functional RPA complex proteins in Saccharomyces cerevisiaeEfficient nuclear transport of structurally disturbed cargo: mutations in a cargo protein switch its cognate karyopherin.SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stabilityChanges in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation.Timely activation of budding yeast APCCdh1 involves degradation of its inhibitor, Acm1, by an unconventional proteolytic mechanism.Endoreduplication and activation of the anaphase-promoting complex during symbiotic cell development.Alleviating neuropathic pain mechanical allodynia by increasing Cdh1 in the anterior cingulate cortex.An APC/C-Cdh1 Biosensor Reveals the Dynamics of Cdh1 Inactivation at the G1/S TransitionIdentification of yeast IQGAP (Iqg1p) as an anaphase-promoting-complex substrate and its role in actomyosin-ring-independent cytokinesis.Nucleolar asymmetry and the importance of septin integrity upon cell cycle arrestRegulation of APC/C-Cdh1 and its function in neuronal survivalMutually dependent degradation of Ama1p and Cdc20p terminates APC/C ubiquitin ligase activity at the completion of meiotic development in yeast.Dbf2-Mob1 drives relocalization of protein phosphatase Cdc14 to the cytoplasm during exit from mitosisThe emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression.APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy.
P2860
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P2860
Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1)
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cell cycle-dependent nuclear e ...... he inactivation of APC/C(Cdh1)
@ast
Cell cycle-dependent nuclear e ...... he inactivation of APC/C(Cdh1)
@en
Cell cycle-dependent nuclear e ...... e inactivation of APC/C(Cdh1).
@nl
type
label
Cell cycle-dependent nuclear e ...... he inactivation of APC/C(Cdh1)
@ast
Cell cycle-dependent nuclear e ...... he inactivation of APC/C(Cdh1)
@en
Cell cycle-dependent nuclear e ...... e inactivation of APC/C(Cdh1).
@nl
prefLabel
Cell cycle-dependent nuclear e ...... he inactivation of APC/C(Cdh1)
@ast
Cell cycle-dependent nuclear e ...... he inactivation of APC/C(Cdh1)
@en
Cell cycle-dependent nuclear e ...... e inactivation of APC/C(Cdh1).
@nl
P2093
P2860
P3181
P356
P1433
P1476
Cell cycle-dependent nuclear e ...... he inactivation of APC/C(Cdh1)
@en
P2093
Frank van Drogen
Malika Jaquenoud
Matthias Peter
P2860
P304
P3181
P356
10.1093/EMBOJ/CDF634
P407
P577
2002-12-02T00:00:00Z