RPA regulates telomerase action by providing Est1p access to chromosome ends.
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityReplication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeresCellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpointsEvidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNARPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage responseStructure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplexThe yeast Pif1p helicase removes telomerase from telomeric DNA.Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation.The U3 small nucleolar ribonucleoprotein component Imp4p is a telomeric DNA-binding protein.Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replicationRPA facilitates telomerase activity at chromosome ends in budding and fission yeastsRPA-like proteins mediate yeast telomere function.The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisHuman replication protein A unfolds telomeric G-quadruplexesRPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome endsCell cycle-dependent regulation of yeast telomerase by Ku.Dynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiaeTERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.Analysis of expressed sequence tags from Rhynchosciara americana salivary glands.Vertebrate POT1 restricts G-overhang length and prevents activation of a telomeric DNA damage checkpoint but is dispensable for overhang protectionTetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint.Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere lossDistinct roles for yeast Stn1 in telomere capping and telomerase inhibition.Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres.Replication protein A: directing traffic at the intersection of replication and repair.A coming-of-age story: activation-induced cytidine deaminase turns 10.Insights into Cdc13 dependent telomere length regulation.Protection and replication of telomeres in fission yeast.Structural insights into G-quadruplexes: towards new anticancer drugs.Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNAATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in ArabidopsisThe principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeresXenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract.RPA and POT1: friends or foes at telomeres?A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening.Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair.The DNA damage response and checkpoint adaptation in Saccharomyces cerevisiae: distinct roles for the replication protein A2 (Rfa2) N-terminus.RPA-1 from Leishmania amazonensis (LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain.
P2860
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P2860
RPA regulates telomerase action by providing Est1p access to chromosome ends.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@ast
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@en
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@nl
type
label
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@ast
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@en
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@nl
prefLabel
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@ast
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@en
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@nl
P2093
P356
P1433
P1476
RPA regulates telomerase action by providing Est1p access to chromosome ends.
@en
P2093
Eric Gilson
Pierre Luciano
Sylvine Guillot
Vanessa Brevet
Vera Schramke
Vincent Géli
Yves Corda
P2888
P356
10.1038/NG1284
P407
P577
2004-01-01T00:00:00Z
P5875
P6179
1019343262