Cell cycle-dependent regulation of yeast telomerase by Ku.
about
Human Ku70/80 interacts directly with hTR, the RNA component of human telomeraseFinding the end: recruitment of telomerase to telomeresInhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity.The yeast Pif1p helicase removes telomerase from telomeric DNA.TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeresRvb2/reptin physically associates with telomerase in budding yeast.PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase.Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation.Yeast transcription termination factor Rtt103 functions in DNA damage responseChromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p.Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex.Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replicationTel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast.RPA facilitates telomerase activity at chromosome ends in budding and fission yeastsTelomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome endsRecruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeastTwo pathways recruit telomerase to Saccharomyces cerevisiae telomeresThe Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitroTERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome endsProtein kinase C alpha signaling inhibits cyclin D1 translation in intestinal epithelial cellsThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisThe Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae.Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency.Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP.Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model.RNA recognition by the DNA end-binding Ku heterodimer.An RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance.Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase.Telomerase deficiency affects the formation of chromosomal translocations by homologous recombination in Saccharomyces cerevisiae.Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres.Comparative biology of telomeres: where plants stand.A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress.Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance.21st Century Genetics: Mass Spectrometry of Yeast Telomerase.Protection and replication of telomeres in fission yeast.Ku must load directly onto the chromosome end in order to mediate its telomeric functions.The budding yeast nucleus.The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeresThe biogenesis and regulation of telomerase holoenzymes
P2860
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P2860
Cell cycle-dependent regulation of yeast telomerase by Ku.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
name
Cell cycle-dependent regulation of yeast telomerase by Ku.
@ast
Cell cycle-dependent regulation of yeast telomerase by Ku.
@en
type
label
Cell cycle-dependent regulation of yeast telomerase by Ku.
@ast
Cell cycle-dependent regulation of yeast telomerase by Ku.
@en
prefLabel
Cell cycle-dependent regulation of yeast telomerase by Ku.
@ast
Cell cycle-dependent regulation of yeast telomerase by Ku.
@en
P2093
P2860
P356
P1476
Cell cycle-dependent regulation of yeast telomerase by Ku.
@en
P2093
Andrew K P Taggart
Timothy S Fisher
Virginia A Zakian
P2860
P2888
P304
P356
10.1038/NSMB854
P577
2004-11-07T00:00:00Z
P6179
1020000089