Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily
about
LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell linesR-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signalingNeonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distensionLGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signalingIdentification and characterization of a second melanin-concentrating hormone receptor, MCH-2RLGR4 and Its Role in Intestinal Protection and Energy MetabolismA rapid and affordable screening platform for membrane protein trafficking.Identification and structural characterization of the neuronal luteinizing hormone receptor associated with sensory systemsIdentification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociceptionHuman intestinal tissue with adult stem cell properties derived from pluripotent stem cells.Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development.Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster.Intestinal stem cell marker LGR5 expression during gastric carcinogenesis.The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment.Lgr5 is a potential prognostic marker in patients with cervical carcinoma.Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness.Expression and clinical significance of SALL4 and LGR5 in patients with lung cancerThe R-spondin family of proteins: emerging regulators of WNT signaling.LGR5 is a promising biomarker for patients with stage I and II gastric cancerStructure and function of LGR5: an enigmatic G-protein coupled receptor marking stem cells.LGR5 promotes the proliferation of colorectal cancer cells via the Wnt/β-catenin signaling pathway.Correlation of Musashi-1, Lgr5, and pEGFR expressions in human small intestinal adenocarcinomas.LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region.Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse.Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells.R-Spondin1/LGR5 Activates TGFβ Signaling and Suppresses Colon Cancer Metastasis.Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression.Leucine-rich G Protein-coupled Receptor-5 Is Significantly Increased in the Aqueous Humor of Human Eye with Proliferative Diabetic Retinopathy.
P2860
Q21560941-309EDB52-11EC-47F5-A1CF-74DC6F0B0847Q24307371-32159B81-F62C-40DB-8D4F-4365CF33A875Q24561753-2BE2E7BF-A761-4D23-8135-211B9AC4E085Q24606839-32386ED6-EF74-4149-ADB2-D3059A2897F3Q24629423-95FCEAAE-65DB-428C-8808-1F00C48A5913Q26784535-947D0AD5-A5ED-4E5A-9472-0C96E0E6AC13Q27305088-6788062D-EEA8-46D4-9607-E243418B8D54Q28574084-7B2052ED-B512-4905-8147-4BE1706CAEB2Q28577654-69ACD5EE-D02A-4196-9D12-E36C42608C3EQ33729666-0268A3CB-6226-48F6-915D-5A3D180DFE43Q34672491-4EF5864F-9655-4FA5-BF42-9DFF9B68822CQ35028022-37DB5D4E-A235-4682-B870-382605FD9FCEQ35079056-46CF5260-1869-4CC8-B6EF-730155D485A1Q35080956-0B9EB0BC-6CED-4B25-BCA4-B7AEB444CF7FQ35405142-24AC74F2-2200-4732-954A-3164AB885536Q35768268-3E76BC4D-D9CC-4B7B-8FAD-87E98F630241Q36301420-F7193282-EE8B-4B61-A81E-2E9EE98CA1CEQ36335392-3CA27184-2BBE-4481-B575-AAB80E224E0BQ36392765-D1E3BE35-755C-4060-8524-7615E4D2A423Q36563241-DB31F614-9047-4DBD-9E4B-0B9CCE43524BQ38200040-77E13B7F-7A8D-4DE3-A85C-9887689CFAD1Q38857274-B1A0EA8F-D688-4B32-80D9-A025AC2099C7Q38899681-2D7C8B7E-2093-4F45-94FD-934E755469ECQ41408678-CFBF653D-AD01-4BFF-9BBA-252A72899CAEQ41746302-916FD685-61A8-4357-898A-865FD1E45427Q41831171-78C82DB0-1A8E-4AEA-8F31-68C49D97581AQ47216766-9635109C-0C7A-4A0D-AE11-4BAB8B53D35BQ47758650-7BDA3E9F-4011-4576-A337-CF9326B7C5B6Q49569472-C37C532A-17EF-4286-94BF-3A0D93EB2E83Q55689524-1DEC35C7-1177-4C42-B87B-A4B69CC52A40
P2860
Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily
description
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Juni 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/06/18)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/06/18)
@nl
наукова стаття, опублікована в червні 1998
@uk
مقالة علمية (نشرت في 18-6-1998)
@ar
name
Identification and cloning of ...... ein hormone receptor subfamily
@ast
Identification and cloning of ...... ein hormone receptor subfamily
@en
Identification and cloning of ...... ein hormone receptor subfamily
@nl
type
label
Identification and cloning of ...... ein hormone receptor subfamily
@ast
Identification and cloning of ...... ein hormone receptor subfamily
@en
Identification and cloning of ...... ein hormone receptor subfamily
@nl
prefLabel
Identification and cloning of ...... ein hormone receptor subfamily
@ast
Identification and cloning of ...... ein hormone receptor subfamily
@en
Identification and cloning of ...... ein hormone receptor subfamily
@nl
P2093
P921
P356
P1476
Identification and cloning of ...... ein hormone receptor subfamily
@en
P2093
C. T. Caskey
T. McDonald
P304
P356
10.1006/BBRC.1998.8774
P407
P577
1998-06-18T00:00:00Z